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Vinpocetine does not fully support a benefit in either dementia or stroke. [12] [9] [13] As of 2003, three controlled clinical trials had tested "older adults with memory problems". [14] Vinpocetine has also been studied for the prevention and recovery of acquired hearing loss in a phase II, longitudinal and prospective open clinical study on ...
Vinca alkaloids are used in chemotherapy for cancer. They are a class of cell cycle–specific cytotoxic drugs that work by inhibiting the ability of cancer cells to divide: Acting upon tubulin, they prevent it from forming into microtubules, a necessary component for cellular division. [13]
Ionizing radiation may be used to treat other cancers, but this may, in some cases, induce a second form of cancer. [74] Radiation can cause cancer in most parts of the body, in all animals, and at any age, although radiation-induced solid tumors usually take 10–15 years, and can take up to 40 years, to become clinically manifest, and ...
The chemical, which is the active ingredient in the weed killer Roundup, can allegedly cause cancer. The oat products tested were made by General Mills, including several Cheerios varieties and ...
The study, conducted in a lab funded by the National Cancer Institute, focused on the role of lipids, also known as fats, in the microenvironments around colon cancer tumors.
Vinpocetine is a synthetic derivative of vincamine used for cerebrovascular diseases and as dietary supplement. [4] Vincamine derivatives have been also studied as anti addictive [ 5 ] and antidiabetic [ 6 ] agents.
The same group has reported on the importance of exosomes in the TME and how these vesicles, shed by adipocytes, can carry a specific molecular cargo that causes metabolic changes in the cell, leading to pro-metastatic changes in the recipient breast cancer cells.
Cells contained in tumor microenvironment are able to produce cytokines which can cause apoptosis of activated T lymphocyte. [9] Another mechanism of tumor cells to avoid immune system is upregulation of non-classical MHC I (HLA-E, HLA-F, HLA-G) which prevents NK-mediated immune reaction by interaction with NK cells.