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  2. Graves' ophthalmopathy - Wikipedia

    en.wikipedia.org/wiki/Graves'_ophthalmopathy

    In mild disease, patients present with eyelid retraction. In fact, upper eyelid retraction is the most common ocular sign of Graves' orbitopathy. This finding is associated with lid lag on infraduction (Von Graefe's sign), eye globe lag on supraduction (Kocher's sign), a widened palpebral fissure during fixation (Dalrymple's sign) and an incapacity of closing the eyelids completely ...

  3. Chronic limb threatening ischemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_limb_threatening...

    Rest pain is a continuous burning pain of the lower leg or feet. It begins, or is aggravated, after reclining or elevating the limb and is relieved by sitting or standing. It is more severe than intermittent claudication, which is also a pain in the legs from arterial insufficiency. [citation needed]

  4. Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Graves'_disease

    Class 1: Only signs (limited to upper lid retraction and stare, with or without lid lag) Class 2: Soft tissue involvement (oedema of conjunctivae and lids, conjunctival injection, etc.) Class 3: Proptosis; Class 4: Extraocular muscle involvement (usually with diplopia) Class 5: Corneal involvement (primarily due to lagophthalmos)

  5. Parinaud's syndrome - Wikipedia

    en.wikipedia.org/wiki/Parinaud's_syndrome

    Convergence-retraction nystagmus: Attempts at upward gaze often produce this phenomenon. On fast up-gaze, the eyes pull in and the globes retract. The easiest way to bring out this reaction is to ask the patient to follow down-going stripes on an optokinetic drum. [9] Eyelid retraction (Collier's sign)

  6. File:Proptosis and lid retraction from Graves' Disease.jpg

    en.wikipedia.org/wiki/File:Proptosis_and_lid...

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  7. Von Graefe's sign - Wikipedia

    en.wikipedia.org/wiki/Von_Graefe's_sign

    It is a dynamic sign, whereas lid lag is a static sign which may also be present in cicatricial eyelid retraction or congenital ptosis. A pseudo Graefe's sign (pseudo lid lag) shows a similar lag, but is due to aberrant regeneration of fibres of the oculomotor nerve (III) into the elevator of the upper lid. [2] It occurs in paramyotonia ...

  8. List of eponymous medical signs - Wikipedia

    en.wikipedia.org/wiki/List_of_eponymous_medical...

    hip and knee fully flexed, extension of knee elicits pain and/or opisthotonus Kocher's sign: Emil Theodor Kocher: ophthalmology, endocrinology: Hyperthyroidism, Basedow's disease, In fixation on a fast upwards movement there occurs a convulsive retraction of the eyelid Koebner's phenomenon: Heinrich Koebner: dermatology: various conditions ...

  9. Limb infarction - Wikipedia

    en.wikipedia.org/wiki/Limb_infarction

    The major tissues affected are nerves and muscles, where irreversible damage starts to occur after 4–6 hours of cessation of blood supply. [4] Skeletal muscle, the major tissue affected, is still relatively resistant to infarction compared to the heart and brain because its ability to rely on anaerobic metabolism by glycogen stored in the cells may supply the muscle tissue long enough for ...