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Neopentyl glycol (IUPAC name: 2,2-dimethylpropane-1,3-diol) is an organic chemical compound. It is used in the synthesis of polyesters , paints , lubricants , and plasticizers . When used in the manufacture of polyesters, it enhances the stability of the product towards heat, light, and water.
1,3-Propanediol is mainly produced by the hydration of acrolein. An alternative route involves the hydroformylation of ethylene oxide to form 3-hydroxypropionaldehyde. The aldehyde is subsequently hydrogenated to give 1,3-propanediol. Biotechnological routes are also known. [2] Two other routes involve bioprocessing by certain micro-organisms:
The most common side effects include decreased hemoglobin, anemia, fatigue, increased creatinine, headache, dizziness, increased glucose, and nausea. [ 10 ] Belzutifan was approved for medical use in the United States in August 2021, [ 10 ] [ 18 ] in the United Kingdom in May 2022, [ 8 ] and in the European Union in February 2025.
Bronopol (INN; chemical name 2-bromo-2-nitropropane-1,3-diol) is an organic compound that is used as an antimicrobial. It is a white solid although commercial samples appear yellow. It is a white solid although commercial samples appear yellow.
Structure of (C 3 H 6 S 2) 2, the oxidized "dimer" of 1,3-propanedithiol. [4] 1,3-Propanedithiol is used in the synthesis of tiapamil. 1,3-Propanedithiol reacts with metal ions to form dithiolates. Illustrative is the synthesis of the derivative diiron propanedithiolate hexacarbonyl upon reaction with triiron dodecacarbonyl: [5] Fe 3 (CO) 12 ...
Allyl alcohol (IUPAC name: prop-2-en-1-ol) is an organic compound with the structural formula CH 2 =CHCH 2 OH. Like many alcohols , it is a water-soluble, colourless liquid. It is more toxic than typical small alcohols.
CDPPB is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR 5. [1] [2] [3] It has antipsychotic effects in animal models, [4] and mGluR 5 modulators are under investigation as potential drugs for the treatment of schizophrenia, [5] as well as other applications.
In enzymology, a 1,3-propanediol dehydrogenase (EC 1.1.1.202) is an enzyme that catalyzes the chemical reaction. propane-1,3-diol + NAD + 3-hydroxypropanal + NADH + H +. Thus, the two substrates of this enzyme are propane-1,3-diol and NAD +, whereas its 3 products are 3-hydroxypropanal, NADH, and H +.
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