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Phytophotodermatitis, also known as berloque dermatitis, [1] [2] [3] margarita photodermatitis, [4] [5] lime disease [6] or lime phytodermatitis [6] is a cutaneous phototoxic inflammatory reaction resulting from contact with a light-sensitizing botanical agent (such as lime juice) followed by exposure to ultraviolet A (UV-A) light (from the sun, for instance).
Photodermatitis can also be caused by plants such as Ammi majus, parsnip, giant hogweed (Heracleum mantegazzianum), common rue (Ruta graveolens), and Dictamnus, a genus of flowering plants in the family Rutaceae with a single species Dictamnus albus, commonly called the burning bush. Photodermatitis caused by plants is called phytophotodermatitis.
Prolonged exposure is associated with the development of skin cancers, photoaging or premature skin aging, immune suppression, and eye diseases like cataracts. [ 14 ] [ 15 ] Given these dual effects, public health organizations emphasize the importance of striking a balance between the benefits and risks of UV exposure.
PLE does not increase the risk of lupus. [15] Other similar appearing conditions are solar urticaria, which has a shorter duration, the eczema-like condition, photosensitive dermatitis, [2] and photosensitivity drug reaction. [9] Prickly heat, which is caused by warm weather or heat is not the same as PLE. [5]
The inner-ear condition Ménière's disease can be aggravated by flicker. Sufferers of vertigo are recommended to not use fluorescent lights. Polymorphous light eruption is a condition affecting the skin thought to be caused by an adverse reaction to ultraviolet light. Its prevalence across Europe is 10-20% of the population.
For years, a man from Bangladesh lived with "tree man" syndrome.. Abul Bajandar's hands and feet grew foot-long "roots" that left him unable to feed himself, move around, work or wear normal clothing.
Many synthetic compounds, including drug substances like tetracyclines or fluoroquinolones, are known to cause these effects. Surface contact with some such chemicals causes photodermatitis, and many plants cause phytophotodermatitis. Light-induced toxicity is a common phenomenon in humans; however, it also occurs in other animals.
This is an accepted version of this page This is the latest accepted revision, reviewed on 2 March 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
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