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The partial thromboplastin time (PTT), also known as the activated partial thromboplastin time (aPTT or APTT), is a blood test that characterizes coagulation of the blood.A historical name for this measure is the Kaolin-cephalin clotting time (KCCT), [1] reflecting kaolin and cephalin as materials historically used in the test.
The required time for the blood to clot is measured. [5] There are several other methods, including testing for those on blood thinners, such as heparin or warfarin. Activated partial thromboplastin time (aPTT) is used for heparin studies and the normal range is 20–36 seconds, depending upon which type of activator is used in the study. [6]
The thrombin time (TT), also known as the thrombin clotting time (TCT), is a blood test that measures the time it takes for a clot to form in the plasma of a blood sample containing anticoagulant, after an excess of thrombin has been added. [1] It is used to diagnose blood coagulation disorders and to assess the effectiveness of fibrinolytic ...
The basic purpose of these tests is to determine the cause of prolongation of Prothrombin Time (PT), Partial Thromboplastin Time, or sometimes of thrombin time (TT). Mixing studies take advantage of the fact that factor levels that are 50 percent of normal should give a normal Prothrombin time (PT) or Partial thromboplastin time (PTT) result. [2]
Prothrombin time (PT) 10, [18] 11, [14] [150] 12 [15] 13, [18] 13.5, [150] 14, [15] 15 [14] s: PT reference varies between laboratory kits – INR is standardised INR: 0.9 [5] 1.2 [5] The INR is a corrected ratio of a patient's PT to normal Activated partial thromboplastin time (APTT) 18, [15] 30 [5] [18] 28, [15] 42, [5] 45 [18] s: Thrombin ...
Activated clotting time (ACT), also known as activated coagulation time, is a test of coagulation. [1] [2]The ACT test can be used to monitor anticoagulation effects, such as from high-dose heparin before, during, and shortly after procedures that require intense anticoagulant administration, such as cardiac bypass, interventional cardiology, thrombolysis, extra-corporeal membrane oxygenation ...
[5] nAPCsr values range from 0 to 10. [5] Opposite to the case of the APCsr with the aPTT-based APC resistance test, higher nAPCsr values indicate greater APC resistance. [5] [8] This is the result of the fact that APC prolongs the aPTT but inhibits thrombin generation. [8]
Primary fibrinogenolysis is the pathological lysis of fibrinogen characterized with a low fibrinogen, high fibrin degradation products, prolonged prothrombin time and activated partial thromboplastin time, a normal platelet count and absence of microcirculatory thrombosis. [1]