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Peeling skin syndrome 1 is caused by a genetic defect in the corneodesmosin (CDSN) gene. This gene localizes to the human epidermis and other epithelia. The protein experiences a chain of cleavages during corneocyte maturation. [6] Its symptoms include short stature, abnormality of metabolism/homeostasis, scaling skin, pruritus, erythema ...
Scale forms on the skin surface in various disease settings, and is the result of abnormal desquamation. In pathologic desquamation, such as that seen in X-linked ichthyosis, the stratum corneum becomes thicker (hyperkeratosis), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, which forms visible scales. [2]
Dyshidrosis. Dyshidrosis is a type of dermatitis, characterized by itchy vesicles of 1–2 mm in size, on the palms of the hands, sides of fingers, or bottoms of the feet. [8] Outbreaks usually conclude within three to four weeks, but often recur. [4] [8] Repeated attacks may result in fissures and skin thickening. [7]
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Keratolysis exfoliativa (also known as" lamellar dyshidrosis ", [1] " recurrent focal palmar peeling ", [2] " recurrent palmar peeling " [1] : 212 [2]) is a sometimes harmless, sometimes painful skin condition that can affect the focal surface of the fingers and/or the palm or soles of the feet. It is often misdiagnosed as chronic contact ...
Dermatophagia. Dermatophagia (from Ancient Greek δέρμα — lit. skin and φαγεία lit. eating) or dermatodaxia (from δήξις, lit. biting) [3] is a compulsion disorder of gnawing or biting one's own skin, most commonly at the fingers. This action can either be conscious or unconscious [4] and it is considered to be a type of pica.
Wrinkly skin syndrome (WSS) is a rare genetic condition characterized by sagging, wrinkled skin, low skin elasticity, and delayed fontanelle (soft spot) closure, along with a range of other symptoms. [1] The disorder exhibits an autosomal recessive inheritance pattern with mutations in the ATP6V0A2 gene, leading to abnormal glycosylation events ...
Skeeter syndrome. Skeeter syndrome (papular urticaria) is a localized severe allergic reaction to mosquito bites, [1] consisting of inflammation, peeling skin, blistering, ulceration and sometimes fever. It is caused by allergenic polypeptides in mosquito saliva, and therefore is not contagious. [2] It is one of several forms, being one of the ...