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The atypical antipsychotics ( AAP ), also known as second generation antipsychotics ( SGAs) and serotonin –dopamine antagonists ( SDAs ), [ 1][ 2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely ...
Typical antipsychotic. Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia ). Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions.
Typical antipsychotics have been around longer and are known as first-generation antipsychotics. Atypical antipsychotics are a newer class, known as second-generation antipsychotics. While typical ...
Clozapine is a psychiatric medication and was the first atypical antipsychotic (also called second-generation antipsychotic) to be discovered. [6] It is primarily used to treat people with schizophrenia and schizoaffective disorder who have had an inadequate response to two other antipsychotics, or who have been unable to tolerate other drugs due to extrapyramidal side effects.
First-generation antipsychotics (e.g., chlorpromazine), known as typical antipsychotics, were first introduced in the 1950s, and others were developed until the early 1970s. [12] Second-generation antipsychotics, known as atypical antipsychotics, arrived with the introduction of clozapine in the early 1970s followed by others (e.g., risperidone ...
Cariprazine, sold under the brand name Vraylar among others, is an atypical antipsychotic developed by Gedeon Richter, [ 8 ] which is used in the treatment of schizophrenia, bipolar mania, [ 9 ] bipolar depression, [ 10 ] and major depressive disorder. [ 6 ]
The second-generation iPhone SE (also known as the iPhone SE 2 or the iPhone SE 2020) is a smartphone designed, developed, and marketed by Apple Inc. It is part of the 13th generation of the iPhone, alongside the iPhone 11 and 11 Pro/Pro Max models. Apple announced it on April 15, 2020, coinciding with the discontinuation of the iPhone 8 and 8 ...
A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist ( DRA ), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia, bipolar disorder, and stimulant psychosis. [ 1]