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  2. Neurofibromatosis - Wikipedia

    en.wikipedia.org/wiki/Neurofibromatosis

    Neurofibromatosis type 1 in early life may cause learning and behavior problems – about 60% of children who have NF1 have mild difficulty in school. [7] Signs the individual might have are as follows: [8] [9] Six or more light brown dermatological spots ("café au lait spots") At least two neurofibromas; At least two growths on the eye's iris

  3. Neurofibromatosis type I - Wikipedia

    en.wikipedia.org/wiki/Neurofibromatosis_type_I

    Café au lait spot characteristic of NF1 Diagnostic criteria of neurofibromatosis type I, requiring at least 2 of the mentioned items. [6]The following is a list of conditions and complications associated with NF-1, and, where available, age range of onset and progressive development, occurrence percentage of NF-1 population, method of earliest diagnosis, and treatments and related medical ...

  4. Familial multiple cafe-au-lait spots - Wikipedia

    en.wikipedia.org/wiki/Familial_multiple_cafe-au...

    Deaths. -. Familial multiple cafe au lait spots, also known as autosomal dominant multiple cafe au lait spots or neurofibromatosis type 6, [2] is a rare, cutaneous genetic disorder which is characterized by the hereditary cutaneous presence of several cafe-au-lait spots without any other symptoms of neurofibromatosis. [3]

  5. Neurofibromatosis type II - Wikipedia

    en.wikipedia.org/wiki/Neurofibromatosis_type_II

    Neurofibromatosis type II (also known as MISME syndrome – multiple inherited schwannomas, meningiomas, and ependymomas) is a genetic condition that may be inherited or may arise spontaneously, and causes benign tumors of the brain, spinal cord, and peripheral nerves. The types of tumors frequently associated with NF2 include vestibular ...

  6. Café au lait spot - Wikipedia

    en.wikipedia.org/wiki/Café_au_lait_spot

    Diagnosis is visual with measurement of spot size. The number of spots can have clinical significance for diagnosis of associated disorders such as neurofibromatosis type I. Six or more spots of at least 5 mm in diameter in pre-pubertal children and at least 15 mm in post-pubertal individuals is one of the major diagnostic criteria for NF1. [10]

  7. Neurofibroma - Wikipedia

    en.wikipedia.org/wiki/Neurofibroma

    Neurofibroma. A neurofibroma is a benign nerve-sheath tumor in the peripheral nervous system. In 90% of cases, they are found as stand-alone tumors ( solitary neurofibroma, solitary nerve sheath tumor[ 1] or sporadic neurofibroma[ 1] ), while the remainder are found in persons with neurofibromatosis type I (NF1), an autosomal-dominant ...

  8. Neurofibromin - Wikipedia

    en.wikipedia.org/wiki/Neurofibromin

    Main symptoms of neurofibromatosis type I [28] Mutations in NF1 are primarily associated with neurofibromatosis type 1 (NF1, also known as von Recklinghausen syndrome). [6] [7] NF1 is the most common single gene disorder in humans, occurring in about 1 in 2500–3000 births worldwide. [29]

  9. Neuroblastoma - Wikipedia

    en.wikipedia.org/wiki/Neuroblastoma

    Neuroblastoma is the most common cancer in babies and the third-most common cancer in children after leukemia and brain cancer. [5] About one in every 7,000 children is affected at some time. [2] About 90% of cases occur in children less than 5 years old, and it is rare in adults. [2] [3] Of cancer deaths in children, about 15% are due to ...