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Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body. [1][7][2] One nanogram per millilitre (1 ng/mL) is equivalent to 2.5 nanomoles per litre (2.5 nmol/L). Severe deficiency: <12 ng/mL = <30 nmol/L[2] Deficiency ...
The name 25 (OH)D refers to any combination of calcifediol (25-hydroxy-cholecalciferol), derived from vitamin D 3, and ercalcidiol (25-hydroxy-ergocalciferol), [1] derived from vitamin D 2. The first of these (also known as 25-hydroxy vitamin D3) is made by the body, or is sourced from certain animal foods or cholecalciferol supplements.
Vitamin D 5. sitocalciferol. (made from 7-dehydrositosterol) Several forms (vitamers) of vitamin D exist, with the two major forms being vitamin D 2 or ergocalciferol, and vitamin D 3 or cholecalciferol. [ 1 ] The term 'vitamin D' refers to either D 2 or D 3, or both, and is known collectively as calciferol.
Healthcare professionals can diagnose vitamin D deficiency with a 25-hydroxy vitamin D blood test. This test checks for 25-hydroxyvitamin D, a common form of vitamin D that circulates in the blood.
It is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D (25(OH)D) in plasma, which is the most accurate measure of stores of vitamin D in the body. Deficiency is defined as less than 10 ng/mL, and insufficiency in the range of 10–30 ng/mL.
These two forms of vitamin D are metabolized in the liver and stored as 25-hydroxyvitamin D. [4] Before biological use, the storage form must be converted into an active form. One common active form is 1,25-dihydroxyvitamin D. [ 4 ] The term vitamin D in this article means cholecalciferol, ergocalciferol, 25-hydroxyvitamin D, and the active forms.
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