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Hereditary diseases that cause damage to the liver include hemochromatosis, [10] involving accumulation of iron in the body, and Wilson's disease. Liver damage is also a clinical feature of alpha 1-antitrypsin deficiency [ 11 ] and glycogen storage disease type II .
Stages of metabolic dysfunction–associated steatotic liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis. Metabolic dysfunction–associated steatotic liver disease ( MASLD ), previously known as non-alcoholic fatty liver disease ( NAFLD ), [ a ] is a type of chronic liver disease.
Chronic liver disease takes several years to develop and the condition may not be recognised unless there is clinical awareness of subtle signs and investigation of abnormal liver function tests. Testing for chronic liver disease involves blood tests, imaging including ultrasound, and a biopsy of the liver. The liver biopsy is a simple ...
Fatty liver disease ( FLD ), also known as hepatic steatosis and steatotic liver disease ( SLD ), is a condition where excess fat builds up in the liver. [ 1] Often there are no or few symptoms. [ 1][ 2] Occasionally there may be tiredness or pain in the upper right side of the abdomen. [ 1] Complications may include cirrhosis, liver cancer ...
Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is a condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue ( fibrosis) and regenerative nodules as a result of chronic liver disease. [ 6 ][ 7 ][ 8 ] Damage to the liver leads to repair of liver tissue ...
Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80–90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum ...
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