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  2. Diabetic ketoacidosis - Wikipedia

    en.wikipedia.org/wiki/Diabetic_ketoacidosis

    In general, insulin is given at 0.1 units/kg per hour to reduce blood sugars and suppress ketone production. Guidelines differ as to which dose to use when blood sugar levels start falling; American guidelines recommend reducing the dose of insulin once glucose falls below 16.6 mmol/L (300 mg/dL) [3] and UK guidelines at 14 mmol/L (253 mg/dL). [6]

  3. Ketosis - Wikipedia

    en.wikipedia.org/wiki/Ketosis

    Ketosis is a metabolic state characterized by elevated levels of ketone bodies in the blood or urine. Physiological ketosis is a normal response to low glucose availability. In physiological ketosis, ketones in the blood are elevated above baseline levels, but the body's acid–base homeostasis is maintained.

  4. Ketotic hypoglycemia - Wikipedia

    en.wikipedia.org/wiki/Ketotic_hypoglycemia

    Ketotic hypoglycemia refers to any circumstance in which low blood glucose is accompanied by ketosis, the presence of ketone bodies (such as beta-hydroxybutyrate) in the blood or urine. This state can be either physiologic or pathologic; physiologic ketotic hypoglycemia is a common cause of hypoglycemia in children, often in response to ...

  5. Ketogenesis - Wikipedia

    en.wikipedia.org/wiki/Ketogenesis

    The accumulation of acetyl-CoA in turn produces excess ketone bodies through ketogenesis. [11] The result is a rate of ketone production higher than the rate of ketone disposal, and a decrease in blood pH. [12] In extreme cases the resulting acetone can be detected in the patient's breath as a faint, sweet odor.

  6. Ketonuria - Wikipedia

    en.wikipedia.org/wiki/Ketonuria

    In conditions associated with acidosis, urinary ketones are tested to assess the severity of acidosis and to monitor treatment response. Urine ketones appear before there is any significant increase in blood ketones; [11] therefore, urine ketone measurement is especially helpful in emergency situations.

  7. Ketoacidosis - Wikipedia

    en.wikipedia.org/wiki/Ketoacidosis

    Blood tests for the diagnosis of diabetic ketoacidosis measure glycemia (sugar level), pH (blood acidity), and ketone bodies. As urgent medical treatment is often required when DKA is suspected, the tentative diagnosis can be made based on clinical history and by calculating the anion gap from the basic metabolic panel , which would demonstrate ...

  8. Complications of diabetes - Wikipedia

    en.wikipedia.org/wiki/Complications_of_diabetes

    While feeling unwell, Start with regular monitoring of blood glucose levels. In addition to measuring blood or urine ketone concentrations twice a day and more. In case there are ketones, insulin doses should be increased. Patients are also advised to focus on dehydration and go to the hospital in case of frequent vomiting.

  9. Ketogenic diet - Wikipedia

    en.wikipedia.org/wiki/Ketogenic_diet

    These ketone bodies enter the brain and partially substitute for blood glucose as a source of energy. [59] The ketone bodies are possibly anticonvulsant; in animal models, acetoacetate and acetone protect against seizures. The ketogenic diet results in adaptive changes to brain energy metabolism that increase the energy reserves; ketone bodies ...

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