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Chlortalidone is considered a first-line medication for treatment of high blood pressure. [2] Some recommend chlortalidone over hydrochlorothiazide. [1] [15] A meta-analysis of randomized controlled trials found that chlortalidone is more effective than hydrochlorothiazide for lowering blood pressure, while the two drugs have similar toxicity.
May worsen diabetes Thiazides reduce the clearance of uric acid since they compete for the same transporter, and therefore raise the levels of uric acid in the blood. Hence, they are prescribed with caution in patients with gout or hyperuricemia .
Diabetes is very common. The Centers for Disease Control and Prevention (CDC) notes that 38.4 million people in the United States are currently living with diabetes. That’s 11.6 percent of the ...
Very rarely Stevens–Johnson syndrome, liver damage, severe allergy has been reported [17] May lower blood sugar excessively in combination with diabetes medication. [17] Contains a chemical linked to possible birth defects. [ 17 ]
Atenolol/chlorthalidone, also known as co-tenidone, is a combination medication used to treat high blood pressure. [2] [3] It is made up of atenolol, a beta-blocker and chlortalidone, a diuretic. [4] It is not recommended as an initial treatment but may be used in those who are taking atenolol and chlortalidone individually. [5] It is taken by ...
"Chlortalidone has a higher risk of side effects than hydrochlorothiazide." [1] Quote = However, chlorthalidone use is more frequently associated with adverse metabolic effects, particularly hypokalemia and hyponatremia, compared with HCTZ. Doc James (talk · contribs · email) 09:34, 2 November 2019 (UTC) Agreed. That ref is clear.
According to 2021 data by the CDC, approximately 38.4 million people (11.6% of the U.S. population) have diabetes, 8.7 million of whom were undiagnosed but met laboratory criteria for diabetes ...
Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]