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17773 Ensembl ENSG00000168412 ENSMUSG00000054764 UniProt P48039 Q61184 RefSeq (mRNA) NM_005958 NM_008639 RefSeq (protein) NP_005949 NP_032665 Location (UCSC) Chr 4: 186.53 – 186.56 Mb Chr 8: 45.52 – 45.54 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Melatonin receptor type 1A is a protein that in humans is encoded by the MTNR1A gene. Function This gene encodes the MT 1 protein ...
Melatonin receptors are G protein-coupled receptors (GPCR) which bind melatonin. [1] Three types of melatonin receptors have been cloned.The MT 1 (or Mel 1A or MTNR1A) and MT 2 (or Mel 1B or MTNR1B) receptor subtypes are present in humans and other mammals, [2] while an additional melatonin receptor subtype MT 3 (or Mel 1C or MTNR1C) has been identified in amphibia and birds. [3]
n/a Ensembl ENSG00000205362 n/a UniProt P04731 n/a RefSeq (mRNA) NM_005946 n/a RefSeq (protein) NP_005937 n/a Location (UCSC) Chr 16: 56.64 – 56.64 Mb n/a PubMed search n/a Wikidata View/Edit Human Metallothionein-1A is a protein that in humans is encoded by the MT1A gene. References ^ a b c GRCh38: Ensembl release 89: ENSG00000205362 – Ensembl, May 2017 ^ "Human PubMed Reference ...
The melatonin receptors are G protein-coupled receptors and are expressed in various tissues of the body. There are two subtypes of the receptor in humans, melatonin receptor 1 (MT 1) and melatonin receptor 2 (MT 2). [2] Melatonin and melatonin receptor agonists, on market or in clinical trials, all bind to and activate both receptor types. [1]
Stimulation of the melanocortin-4 receptor causes a decrease in appetite and an increase in metabolism of fat and lean body mass, even in a relatively starved state. [21] Conversely, damage to this receptor has been shown to result in morbid obesity, and is the most commonly known cause of monogenic morbid obesity. [ 22 ]
MT 1 protein, see Melatonin receptor 1A Topics referred to by the same term This disambiguation page lists articles associated with the same title formed as a letter–number combination.
This gene encodes the MT 2 protein, one of two high-affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain; however, this detection requires RT-PCR.
The 5-HT 1 receptors are a subfamily of the 5-HT serotonin receptors that bind to the endogenous neurotransmitter serotonin (also known as 5-hydroxytryptamine, or 5-HT). [1] The 5-HT 1 subfamily consists of five G protein-coupled receptors (GPCRs) that share 40% to 63% overall sequence homology, including 5-HT 1A, 5-HT 1B, 5-HT 1D, 5-HT 1E, and 5-HT 1F. [2]