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A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain nerves and blood vessels.
Thick, hyalinised collagen fibres are characteristic of this aberrant healing process. H&E stain. Histologically , keloids are fibrotic tumors characterized by a collection of atypical fibroblasts with excessive deposition of extracellular matrix components, especially collagen , fibronectin , elastin , and proteoglycans .
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Scars form differently based on the location of the injury on the body and the age of the person who was injured. [citation needed] The worse the initial damage is, the worse the scar will generally be. [citation needed] Skin scars occur when the dermis (the deep, thick layer of skin) is damaged.
Fibrosis, also known as fibrotic scarring, is the development of fibrous connective tissue in response to an injury. Fibrosis can be a normal connective tissue deposition or excessive tissue deposition caused by a disease.
A callus (pl.: calluses) is an area of thickened and sometimes hardened skin that forms as a response to repeated friction, pressure, or other irritation. Since repeated contact is required, calluses are most often found on the feet and hands, but they may occur anywhere on the skin.
In all types, some increased fragility occurs, but the degree varies depending on the underlying subtype. The skin may tear and bruise easily, and may heal with abnormal atrophic scars; [45] atrophic scars that look like cigarette paper are a sign seen including in those whose skin might appear otherwise normal.
Aplasia cutis congenita (cutis aplasia, congenital absence of skin, congenital scars) Arteriovenous fistula; Benign neonatal hemangiomatosis; Branchial cyst (branchial cleft cyst) Bronchogenic cyst; Capillary hemangioma (infantile hemangioma, nevus maternus, strawberry hemangioma, strawberry nevus) Cavernous venous malformation