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Aromatic amines are chemicals that are produced when products such as dyes, polyurethane products, and certain pesticides are made. They are also found in cigarette smoke, fuel exhaust, and in overcooked, burned meat. The three types of aromatic amines, monocyclic, polycyclic, and heterocyclic, have all been found in recent studies of breast ...
4,4′-Methylenebis(2-chloroaniline) (also known as MOCA, MBOCA, and bisamine) is a substance used as a curing agent in polyurethane production. [3] MOCA is an aromatic amine which is structurally similar to benzidine, a known human bladder carcinogen.
1-Naphthylamine is an aromatic amine derived from naphthalene. It can cause bladder cancer (transitional cell carcinoma). It crystallizes in colorless needles which melt at 50 °C. It possesses a disagreeable odor, sublimes readily, and turns brown on exposure to air. It is the precursor to a variety of dyes. [2]
These are also known as "indirect-acting" carcinogens. Examples of activation-dependent carcinogens include polycyclic aromatic hydrocarbons (PAHs), heterocyclic aromatic amines, and mycotoxins. Activation-independent carcinogens, or "direct-acting" carcinogens, are those that are capable of directly damaging DNA without any modification to ...
It is an aromatic amine. It is a component of a test for cyanide. ... Benzidine has been linked to bladder and pancreatic cancer. [2] Synthesis and properties
Epidemiological studies linked consumption of well-done meats with increased risk of certain cancers, including cancer of the colon or rectum. [14] A review of research articles on meat consumption and colon cancer estimated that red meat consumption contributed to 7 to 9% of colon cancer cases in European men and women. [citation needed]
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No urinary bladder cancer was found in two of the earlier epidemiological reports of workers exposed to 4-COT in Switzerland and in the US. [6] [7]Stasik et al. obtained similar results in their previous mortality study carried out on a cohort of 335 male employees exposed to 4-COT at plants in Frankfurt.