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Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]
Initial medical treatment consists of prednisone. If ineffective, splenectomy should be considered. [citation needed] If refractory to both these therapies, other options include rituximab, [4] [5] danazol, cyclosphosphamide, azathioprine, or ciclosporin. High-dose intravenous immune globulin may be effective in controlling hemolysis, but the ...
Antiserum or drug treatment should be stopped as soon as possible. [2] [3] Once treatment has stopped, symptoms usually resolve within seven days. [3] Outcomes are generally good. [4] Corticosteroids, antihistamines, and analgesics are the main line of treatment. [3] The choice depends on the severity of the reaction. Prednisone may be used in ...
Prednisone is the drug of choice for PMR, [19] and treatment duration is frequently greater than one year. [14] If the patient does not experience dramatic improvement after three days of 10–20 mg oral prednisone per day, the diagnosis should be reconsidered. [20] Sometimes relief of symptoms occurs in only several hours. [citation needed]
MCTD has no specific treatment. Management should address the individual's primary issues, such as arthritis , skin disease , or visceral involvement. Low-dose glucocorticoids , nonsteroidal anti-inflammatory medications , hydroxychloroquine , or a combination of these therapies can effectively treat many patients.
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First-line treatment for CIDP is currently intravenous immunoglobulin and other treatments include corticosteroids (e.g., prednisone), and plasmapheresis (plasma exchange) which may be prescribed alone or in combination with an immunosuppressant drug. [38]
Growth hormone treatment is a safe and effective therapy that’s often used to treat children and adults with a deficiency in human growth hormone (also known as HGH or somatropin).