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The body (in particular the brain) adapts to the higher sodium concentration. Rapidly lowering the sodium concentration with free water, once this adaptation has occurred, causes water to flow into brain cells and causes them to swell. This can lead to cerebral edema, potentially resulting in seizures, permanent brain damage, or death.
Salt poisoning typically results in a feeling of confusion and jitteriness; more severe intoxication can cause seizures and coma. Death can result if medical intervention is not forthcoming. These symptoms are generally a consequence of hypernatremia – an abnormally high sodium level in the blood. (There are myriad causes of hypernatremia ...
Hypernatremia (high blood sodium level, above 145 mEq/L) causes thirst, and due to brain cell shrinkage may cause confusion, muscle twitching, or spasms. With severe elevation, seizures and comas may occur. [11] [12] Death can be caused by ingestion of large amounts of salt at a time (about 1 g per kg of body weight). [13]
Lower levels of plasma sodium are associated with more severe symptoms. However, mild hyponatremia (plasma sodium levels at 131–135 mmol/L) may be associated with complications and subtle symptoms [14] (for example, increased falls, altered posture and gait, reduced attention, impaired cognition, and possibly higher rates of death). [15] [16]
Examples of causes of provoked seizures that can be corrected include low blood sugar, low blood sodium, febrile seizures in children, and substance/medication use. Starting anti-seizure medications is usually for those with medium to high risk of seizures re-occurring.
Causes of seizures include an imbalance of neurotransmitters (nerve-signaling brain chemicals), brain tumors, stroke, and brain damage from illness or injury, or even a combination of several causes. However, for the majority of seizures, the cause is unable to be determined. [1] Factors that may contribute to a seizure episode include head ...
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Vitamin B12 deficiency was reported to be the cause of seizures for adults [9] [10] and for infants. [11] [12] Folic acid in large amounts was considered to potentially counteract the antiseizure effects of antiepileptic drugs and increase the seizure frequency in some children, although that concern is no longer held by epileptologists. [13]
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