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The tunica externa (Neo-Latin "outer coat"), also known as the tunica adventitia (Neo-Latin "additional coat"), [1] [2] is the outermost tunica (layer) of a blood vessel, surrounding the tunica media. It is mainly composed of collagen and, in arteries, is supported by external elastic lamina. The collagen serves to anchor the blood vessel to ...
Small vessels like vasa vasorum and vasa nervorum are particularly susceptible to external mechanical compression, [10] and thus are involved in pathogenesis of peripheral vascular and nerve diseases. A tear in vasa vasorum situated in tunica media layer of aorta may start pathologic cascade of events leading to aortic dissection. [4]
It consists of circularly arranged elastic fiber, connective tissue and polysaccharide substances; the second and third layer are separated by another thick elastic band called external elastic lamina. [7] The tunica media may (especially in arteries) be rich in vascular smooth muscle, which controls the caliber of the vessel. Veins do not have ...
The tunica intima is well developed, with many smooth muscle cells in the subendothelial connective tissue, and often shows folds in cross section because of the vessel’s contraction with loss of blood pressure at death. Between the intima and the media lies the internal elastic lamina, usually better defined than the elastic laminae of the ...
Diagram of the circulatory system. SVC/IVC - Superior/Inferior vena cava, The heart is the driver of the circulatory system, pumping blood through rhythmic contraction and relaxation. The rate of blood flow out of the heart (often expressed in L/min) is known as the cardiac output (CO).
The tunica intima of muscular arteries features a thin subendothelial layer and a prominent internal elastic lamina, while the media may contain up to 40 layers of large smooth muscle cells interspersed with a variable number of elastic lamellae, depending on the vessel size. Only the larger muscular arteries possess an external elastic lamina.
The tunica intima (Neo-Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein.It is made up of one layer of endothelial cells (and macrophages in areas of disturbed blood flow), [1] [2] and is supported by an internal elastic lamina.
It is unclear whether Mönckeberg's arteriosclerosis is a distinct entity or forms part of a spectrum of vascular calcification that includes atherosclerosis and calcification in the inner layer of the artery wall (tunica intima), calcification of the internal elastic lamina, calcification of cardiac valves and widespread soft tissue ...