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Chromosome 2 is one of the twenty-three pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 2 is the second-largest human chromosome, spanning more than 242 million base pairs [4] and representing almost eight percent of the total DNA in human cells. Chromosome 2 contains the HOXD homeobox gene cluster ...
Genome size ranges (in base pairs) of various life forms. Genome size is the total amount of DNA contained within one copy of a single complete genome.It is typically measured in terms of mass in picograms (trillionths (10 −12) of a gram, abbreviated pg) or less frequently in daltons, or as the total number of nucleotide base pairs, usually in megabases (millions of base pairs, abbreviated ...
C-value is the amount, in picograms, of DNA contained within a haploid nucleus (e.g. a gamete) or one half the amount in a diploid somatic cell of a eukaryotic organism. In some cases (notably among diploid organisms), the terms C-value and genome size are used interchangeably; however, in polyploids the C-value may represent two or more genomes contained within the same nucleus.
The chromid is smaller than the chromosome, and so takes a shorter amount of time to finish replication. For this reason, replication of the chromid is delayed to coordinate replication termination between the chromosome and chromid. [ 25 ]
The Mendelian gene is the classical gene of genetics and it refers to any heritable trait. This is the gene described in The Selfish Gene. [9] More thorough discussions of this version of a gene can be found in the articles Genetics and Gene-centered view of evolution.
Originally, a structure variation affects a sequence length about 1kb to 3Mb, which is larger than SNPs and smaller than chromosome abnormality (though the definitions have some overlap). [1] However, the operational range of structural variants has widened to include events > 50bp. [2]
Gene duplication is a major mechanism through which new genetic material is generated during molecular evolution. For example, the olfactory receptor gene family is one of the best-documented examples of pseudogenes in the human genome. More than 60 percent of the genes in this family are non-functional pseudogenes in humans.
Schematic karyogram of a human, showing a diploid set of all chromosomes, except in case of the sex chromosomes in males (bottom right), where there is an X chromosome and a much smaller Y chromosome, which does not have all the genes that the X chromosome has, making a male hemizygous for those genes.