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  2. Medicare now negotiating price of drug that costs $7,100 in ...

    www.aol.com/medicare-now-negotiating-price-drug...

    Medicare has started its first-ever negotiations with drugmakers over the cost of 10 expensive medications, including Eliquis and Stelara. The prices charged in other countries are not a factor in ...

  3. Elijah Cummings Lower Drug Costs Now Act - Wikipedia

    en.wikipedia.org/wiki/Elijah_Cummings_Lower_Drug...

    Starting in fiscal year 2024, 50 drugs with the same criteria as before would need to have their price negotiated. Any newly approved, single-source, brand name drugs that exceeds a price threshold that the HHS has set that was determined to likely to meet the spending criteria. The negotiated drug prices would have to meet the following criteria:

  4. Factbox-Top Medicare drugs headed for price cuts - AOL

    www.aol.com/news/factbox-top-medicare-drugs...

    Merck & Co's Januvia, used to help lower blood glucose levels in adults with type-2 diabetes, was prescribed to 869,000 patients with Medicare coverage in the year ending June 2023 at a gross cost ...

  5. Explainer-Why the US is negotiating the price of 10 drugs - AOL

    www.aol.com/news/explainer-why-us-negotiating...

    The U.S. government on Tuesday released a list of 10 prescription medicines that will be subject to the first-ever price negotiations by the Medicare health program that covers Americans aged 65 ...

  6. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  7. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    The maximum dose is used, rather than a lower dose, to reduce the number of test subjects (and, among other things, the cost of testing), to detect an effect that might occur only rarely. This type of analysis is also used in establishing chemical residue tolerances in foods. Maximum tolerated dose studies are also done in clinical trials.

  8. Drugmakers to raise US prices on over 250 medicines starting ...

    www.aol.com/news/drugmakers-raise-us-prices-over...

    Drugmakers plan to raise U.S. prices on at least 250 branded medications including Pfizer COVID-19 treatment Paxlovid, Bristol Myers Squibb's cancer cell therapies and vaccines from France's ...

  9. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    In dog testing, this compound with a carboxamide group called 13F, showed a great pharmacokinetical profile, a low clearance and adequate half-life and volume of distribution. Due to the success of finding a stabilizing group, SAR research for S1 binding moiety (p-methoxyphenyl) was discontinued.