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Common side effects of tizanidine include dry mouth, sleepiness, weakness, and dizziness. [5] Serious side effects may include low blood pressure, liver problems, psychosis, and QT prolongation. [5] It is unclear if use in pregnancy and breastfeeding is safe. [6] It is an α 2-adrenergic agonist, but how it works is not entirely clear. [5]
A muscle relaxant is a drug that affects skeletal muscle function and decreases the muscle tone. It may be used to alleviate symptoms such as muscle spasms , pain , and hyperreflexia . The term "muscle relaxant" is used to refer to two major therapeutic groups: neuromuscular blockers and spasmolytics .
It is better to use an effective, well-known analgesic for patients complaining of muscle pain, starting with paracetamol. [16] Although muscle relaxants may have the major side effect of sedation, thiocolchicoside is free from sedation effects, likely due to its lack of potentiation of GABA A receptors. [7]
With an estimated 52.5 million adults in the U.S. affected by arthritis alone and up to 24% of adults experiencing muscle pain during their lifetime, effective topical pain relievers can be life ...
The effect is to prevent spasms of the stomach, intestine or urinary bladder. Both dicyclomine and hyoscyamine are antispasmodic due to their anticholinergic action. [ medical citation needed ] Both of these drugs have side effects common to anticholinergics and can worsen gastroesophageal reflux disease (GERD).
Cyclobenzaprine, sold under several brand names including, historically, Flexeril, is a muscle relaxer used for muscle spasms from musculoskeletal conditions of sudden onset. [5] It is not useful in cerebral palsy. [5] It is taken by mouth. [5] Common side effects include headache, feeling tired, dizziness, and dry mouth. [5]
After the suicide attempt, staff found a box in the resident's room with about 100 Tizanidine tablets in it. The staff knew this particular resident was a suicide risk, according to the survey.
Benzodiazepines are well known for their strong muscle-relaxing properties and can be useful in the treatment of muscle spasms, [24]: 577–578 although tolerance often develops to their muscle relaxant effects. [15] Baclofen [65] or tizanidine are sometimes used as an alternative to benzodiazepines. Tizanidine has been found to have superior ...