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  2. Lotilaner - Wikipedia

    en.wikipedia.org/wiki/Lotilaner

    Lotilaner, sold under the brand name Credelio among others, is a veterinary medication used to control fleas and ticks in dogs and cats. [2] [3] [4] [12] It is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and for the treatment and control of tick infestations including lone star tick (Amblyomma americanum), American dog tick (Dermacentor variabilis ...

  3. Trifluoromethyl group - Wikipedia

    en.wikipedia.org/wiki/Trifluoromethyl_group

    The trifluoromethyl group occurs in certain pharmaceuticals, drugs, and abiotically synthesized natural fluorocarbon based compounds. The medicinal use of the trifloromethyl group dates from 1928, although research became more intense in the mid-1940s. [2]

  4. Trifluoromethylation - Wikipedia

    en.wikipedia.org/wiki/Trifluoromethylation

    The reagent was used in trifluoromethylation of a thiophenolate. S-(trifluoromethyl)dibenzothiophenium tetrafluoroborate is a commercially available and known trifluoromethylation reagent based on the same principle first documented in 1990. [64] [65] In this type of compound sulfur has been replaced by oxygen, selenium and tellurium.

  5. Fluralaner - Wikipedia

    en.wikipedia.org/wiki/Fluralaner

    Bravecto 1-Month was approved by the FDA in November 2024 for the addition of the indication for the treatment and control of Haemaphysalis longicornis (Asian longhorned tick) infestations for one month in dogs and puppies eigjht weeks of age and older, and weighing 4.4 pounds (2.0 kg) or greater.

  6. Trifluoroacetic acid - Wikipedia

    en.wikipedia.org/wiki/Trifluoroacetic_acid

    TFA is a stronger acid than acetic acid, having an acid ionisation constant, K a, that is approximately 34,000 times higher, [3] as the highly electronegative fluorine atoms and consequent electron-withdrawing nature of the trifluoromethyl group weakens the oxygen-hydrogen bond (allowing for greater acidity) and stabilises the anionic conjugate ...

  7. Trifluoronitrosomethane - Wikipedia

    en.wikipedia.org/wiki/Trifluoronitrosomethane

    Trifluoronitrosomethane (commonly abbreviated TFNM) is a toxic organic compound consisting of a trifluoromethyl group covalently bound to a nitroso group. Its distinctive deep blue color is unusual for a gas.

  8. Trifluoromethyltrimethylsilane - Wikipedia

    en.wikipedia.org/wiki/Trifluoromethyltrimethylsilane

    Trifluoromethyltrimethylsilane (known as Ruppert-Prakash reagent, TMSCF 3) is an organosilicon compound with the formula CF 3 Si(CH 3) 3.It is a colorless liquid. The compound is a reagent used in organic chemistry for the introduction of the trifluoromethyl group.

  9. Trifluoromethyl hypofluorite - Wikipedia

    en.wikipedia.org/wiki/Trifluoromethyl_hypofluorite

    Trifluoromethyl hypofluorite is an organofluorine compound with the chemical formula C F 3 OF. It exists as a colorless gas at room temperature and is highly toxic. [1] It is a rare example of a hypofluorite (compound with an O−F bond). It can be seen as a similar chemical compound to methanol where every hydrogen atom is replaced by a ...

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