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Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. It is a colourless solid which is soluble in most common organic solvents , but has very poor solubility in water.
A 2010 review concluded that bisphenol A may increase cancer risk. [63] Several studies show evidence that the formation of prostate cancer in men is directly proportional to BPA exposure. Male subject diagnosed with prostate cancer were found to have higher urine concentration of BPA as opposed to the concentrations found in the control group's.
The risk management portion of the ARECC framework and process emphasizes leadership commitment to the safety and health mission and application of the hierarchy of controls. Commitment includes confirming that all ARECC process steps are being followed and that protection of safety, health, well-being, and productivity is being achieved.
Exceptions include bisphenol S, P, and M. "Bisphenol" is a common name; the letter following denotes the variant, which depends on the additional substituents. Bisphenol A is the most popular representative of the group, with millions of metric tons produced globally in the past decade, often simply called "bisphenol".
They are appointed by the Management Board. The Advisory Forum advises the Executive Director, in particular in drafting a proposal for the EFSA's work programmes. It is composed of representatives of national bodies responsible for risk assessment in the Member States, with observers from Norway, Iceland, Switzerland and the European Commission.
The Weinberg Group is a Washington, DC–based food and drug regulatory consulting group. Founded in 1983, the firm assists pharmaceutical and biotech companies with the "development and implementation of successful and innovative regulatory strategies" and also helps these companies to "remediate, maintain and improve their regulatory compliance."
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On April 18, 2008, Health Canada announced that bisphenol A is "'toxic' to human health". [11] On the same date, Nalgene announced it would phase out production of its Outdoor line of polycarbonate containers containing BPA. [12] Nalgene subsequently adopted Tritan copolyester, a BPA-free copolyester made by Eastman Chemical, as a substitute. [13]