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Bisphenol A (BPA) is a chemical ... Concern is mostly related to its estrogen-like activity, although it can interact with other receptor systems as an endocrine ...
Bisphenol A is an endocrine disruptor that can mimic estrogen and has been shown to cause negative health effects in animal studies. Bisphenol A closely mimics the structure and function of the hormone estradiol by binding to and activating the same estrogen receptor as the natural hormone.
Bisphenols A (BPA), F (BPF) and S (BPS) have been shown to be endocrine disruptors, potentially relating to adverse health effects. [3] [6] Due to its high production volumes, BPA has been characterised as a "pseudo-persistent" chemical, [7] leading to its spreading and potential accumulation in a variety of environmental matrices, even though it has a fairly short half-life.
Phthalates are known as “endocrine disruptors ... BPA: Bisphenol A, or BPA, is a chemical used to make food packaging stronger and less vulnerable to corrosion or breaking down.
A comparison of the structures of the natural estrogen hormone estradiol (left) and one of the nonyl-phenols (right), a xenoestrogen endocrine disruptor. Endocrine disruptors, sometimes also referred to as hormonally active agents, [1] endocrine disrupting chemicals, [2] or endocrine disrupting compounds [3] are chemicals that can interfere with endocrine (or hormonal) systems. [4]
BPA (bisphenol A) is an endocrine disruptor and has been linked with a variety of health issues. Most cans no longer contain BPA; however, it doesn’t hurt to double-check.
Hydrolysis of the ether bonds liberates bisphenol A, which is also strongly suspected of being an endocrine disruptor. [ 12 ] [ 13 ] From the 1990s onward, concern has been raised over the use of BADGE-based epoxy resins in the lining of some cans for foodstuffs, with the chemical being found to leach into foods.
Although research on endocrine disruptors or "obesogens" is still emerging, the public health implications so far have mainly surrounded obesity, diabetes, and cardiovascular disease. Obesity has become a pandemic, increasing for all population groups. From 1980 to 2008, the rates of obesity have doubled for adults and tripled for children. [47]