Search results
Results from the WOW.Com Content Network
Mifepristone, also known by its developmental code name RU-486, is a medication typically used in combination with misoprostol to bring about a medical abortion during pregnancy and manage early miscarriage. [8] This combination is 97% effective during the first 63 days (9 weeks) of pregnancy. [9] It is also effective in the second trimester of ...
In April 1980, as part of a formal research project at Roussel-Uclaf for the development of glucocorticoid receptor antagonists, chemist Georges Teutsch synthesized mifepristone (RU-38486, the 38,486th compound synthesized by Roussel-Uclaf from 1949 to 1980; shortened to RU-486); which was discovered to also be a progesterone receptor antagonist.
After the U.S. Supreme Court's decision to maintain access the abortion pill mifepristone, physicians will be able to keep prescribing the drug as a lower court case on its FDA approval moves ...
The mifepristone-misoprostol combination is, by far, the most recommended drug regimen for medical abortions, but other drug combinations are available. Misoprostol alone, without mifepristone, may be used in some circumstances for medical abortion, and has even been demonstrated to be successful in the second trimester. [ 37 ]
CVS and Walgreens will begin dispensing the abortion pill mifepristone this March, the companies confirmed to TIME. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: ...
Danco Laboratories, a manufacturer of the abortion drug mifepristone, has asked the Supreme Court to reverse a lower court ruling that would restrict access to the drug; the justices could make ...
Examples include the progesterone receptor weak partial agonist mifepristone, the selective progesterone receptor modulator (SPRM) ulipristal acetate, and the silent antagonist aglepristone. [2] [3] In medical abortion, mifepristone is combined with a prostaglandin (e.g., gemeprost), while ulipristal is used for emergency contraception. [4]
Glucocorticoid receptor antagonists: Mifepristone (RU-486) is the primary example of this class, which directly blocks the action of cortisol at its receptor sites. [3] [6] Steroid hormones: Dehydroepiandrosterone (DHEA) has been studied for its potential antiglucocorticoid effects. [3]