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Overactive bladder (OAB) is a common condition where there is a frequent feeling of needing to urinate to a degree that it negatively affects a person's life. [2] The frequent need to urinate may occur during the day, at night, or both. [4]
When the onset is sudden, symptoms include an inability to urinate and lower abdominal pain. [1] When of gradual onset, symptoms may include loss of bladder control, mild lower abdominal pain, and a weak urine stream. [1] Those with long-term problems are at risk of urinary tract infections. [1]
Nocturia is the need of frequent urination at night. [1] The most common cause of this condition for women and children is a urinary tract infection. The most common cause of urinary frequency in older men is an enlarged prostate. [2]
Rare (<0.1%) adverse effects include: Urinary retention; Prolonged QT interval; Torsades de Pointes; Ataxia; Breast enlargement or engorgement; Lactation; Cardiospasm
Nocturia is defined by the International Continence Society (ICS) as "the complaint that the individual has to wake at night one or more times for voiding (i.e., to urinate)". [1] The term is derived from Latin nox – "night", and Greek [τα] ούρα – "urine". Causes are varied and can be difficult to discern. [2]
Oxybutynin, sold under the brand name Ditropan among others, is an anticholinergic medication primarily used to treat overactive bladder.It is widely considered a first-line therapy for overactive bladder due to its well-studied side effect profile, broad applicability, and continued efficacy over long periods of time.
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