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Hemoglobin Lepore syndrome is typically an asymptomatic hemoglobinopathy, which is caused by an autosomal recessive genetic mutation.The Hb Lepore variant, consisting of two normal alpha globin chains (HBA) and two delta-beta globin fusion chains which occurs due to a "crossover" between the delta (HBD) and beta globin (HBB) gene loci during meiosis and was first identified in the Lepore ...
Hemoglobin Constant Spring is a variant of hemoglobin in which a mutation in the alpha globin gene produces an alpha globin chain that is abnormally long. It is the most common nondeletional alpha-thalassemia mutation associated with hemoglobin H disease. [1]
Enlargement of spleen, ascites, jaundice, and the result of destruction of various blood cells by spleen – anemia, leukopenia, thrombocytopenia, gastrointestinal bleeding – may constitute the presenting symptoms. [citation needed]
Iron lung cylinder (black), patient head exposed through sealed opening. Diaphragm (yellow) mechanically extends/retracts, varying cylinder air pressure, causing patient chest to expand (inhale) (top) and contract (exhaling) (bottom) A patient wearing a cuirass respirator 1939 Dutch newsreel on the function of the iron lung
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LP Aquarii is a pulsating variable star in the constellation of Aquarius that varies between magnitudes 6.30 and 6.64. [3] The position of the star near the ecliptic means it is subject to lunar occultations. [11] The star's variability was first detected in the Hipparcos satellite data, and it was given its variable star designation in 1999. [12]
Like many folk songs, "The House of the Rising Sun" is of uncertain authorship. Musicologists say that it is based on the tradition of broadside ballads, and thematically it has some resemblance to the 16th-century ballad "The Unfortunate Rake" (also cited as source material for "St. James Infirmary Blues"), yet there is no evidence suggesting that there is any direct relation. [4]
Sully (also known as Sully: Miracle on the Hudson [6]) is a 2016 American biographical drama film directed by Clint Eastwood and written by Todd Komarnicki, based on the 2009 autobiography Highest Duty by Chesley "Sully" Sullenberger and Jeffrey Zaslow.