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  2. Excitotoxicity - Wikipedia

    en.wikipedia.org/wiki/Excitotoxicity

    Another damaging result of excess calcium in the cytosol is the opening of the mitochondrial permeability transition pore, a pore in the membranes of mitochondria that opens when the organelles absorb too much calcium. Opening of the pore may cause mitochondria to swell and release reactive oxygen species and other proteins that can lead to ...

  3. Hypertension - Wikipedia

    en.wikipedia.org/wiki/Hypertension

    Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. [11] High blood pressure usually does not cause symptoms itself. [1]

  4. What is high blood pressure and why is it called the 'silent ...

    www.aol.com/high-blood-pressure-why-called...

    High blood pressure, also called hypertension, is a vicious and smart adversary.It’s vicious because it greatly increases the odds of heart disease and stroke, some of the leading causes of ...

  5. Glutamate (neurotransmitter) - Wikipedia

    en.wikipedia.org/wiki/Glutamate_(neurotransmitter)

    Glutamate is a very major constituent of a wide variety of proteins; consequently it is one of the most abundant amino acids in the human body. [1] Glutamate is formally classified as a non-essential amino acid, because it can be synthesized (in sufficient quantities for health) from α-ketoglutaric acid, which is produced as part of the citric acid cycle by a series of reactions whose ...

  6. Heart Disease: Does Too Much Caffeine Cause High Blood Pressure?

    www.aol.com/lifestyle/heart-disease-does-too...

    High blood pressure, also known as hypertension, can weaken the heart over time. That may lead to chronic conditions including: That may lead to chronic conditions including: coronary artery disease

  7. Can Dehydration Cause High Blood Pressure? What Experts Say - AOL

    www.aol.com/dehydration-cause-high-blood...

    “This low circulating blood volume causes the release of the hormone vasopressin and when in high enough concentrations, vasopressin constricts blood vessels and causes higher blood pressure ...

  8. Kindling (sedative–hypnotic withdrawal) - Wikipedia

    en.wikipedia.org/wiki/Kindling_(sedative...

    Excessive glutamate release is a known major cause of neuronal cell death. Glutamate causes neurotoxicity due to excitotoxicity and oxidative glutamate toxicity. Evidence from animal studies suggests that some people may be more genetically sensitive to the neurotoxic and brain damage associated with binge drinking regimes.

  9. Complications of hypertension - Wikipedia

    en.wikipedia.org/wiki/Complications_of_hypertension

    The high blood pressure is gradual at early stages and may take at least 10–15 years to fully develop. Besides diabetes, other factors that may also increase high blood pressure include obesity, insulin resistance and high cholesterol levels. In general, fewer than 25 percent of diabetics have good control of their blood pressure. The ...

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