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  2. Threshold potential - Wikipedia

    en.wikipedia.org/wiki/Threshold_potential

    Abnormalities in neuronal excitability have been noted in amyotrophic lateral sclerosis and diabetes patients. While the mechanism ultimately responsible for the variance differs between the two conditions, tests through a response to ischemia indicate a similar resistance, ironically, to ischemia and resulting paresthesias.

  3. Neurocardiology - Wikipedia

    en.wikipedia.org/wiki/Neurocardiology

    The heart is both the source of life and a source of cardiac arrhythmias and complications. The information originates in the brain's cortex and descends down to the hypothalamus. The neural signals are then transferred to the brainstem, followed by the spinal cord—the location from which

  4. M current - Wikipedia

    en.wikipedia.org/wiki/M_current

    M-channels are the reason for slow depolarizations produced by ACh and LHRH in the autonomic ganglia and other specified areas. 1. Initial depolarization of a neuron increases likelihood that M-channels will open. 2. M-channels generate an outward potassium current (I K). 3. Potassium efflux counteracts sodium influx in action potential (AP ...

  5. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    The action potential passes along the cell membrane causing the cell to contract, therefore the activity of the sinoatrial node results in a resting heart rate of roughly 60–100 beats per minute. All cardiac muscle cells are electrically linked to one another, by intercalated discs which allow the action potential to pass from one cell to the ...

  6. Rheobase - Wikipedia

    en.wikipedia.org/wiki/Rheobase

    Nerve excitability examination complements conventional nerve conduction studies by allowing insight into biophysical characteristics of axons, as well as their ion-channel functioning. [10] The protocol is aimed at providing information about nodal as well as internodal ion channels, and the indices are extremely sensitive to axon membrane ...

  7. Action potential - Wikipedia

    en.wikipedia.org/wiki/Action_potential

    Several types of cells support an action potential, such as plant cells, muscle cells, and the specialized cells of the heart (in which occurs the cardiac action potential). However, the main excitable cell is the neuron , which also has the simplest mechanism for the action potential.

  8. Transcranial direct-current stimulation - Wikipedia

    en.wikipedia.org/wiki/Transcranial_direct...

    The way that the stimulation changes brain function is either by causing the neuron’s resting membrane potential to depolarize or hyperpolarize. When positive stimulation (anodal tDCS) is delivered, the current causes a depolarization of the resting membrane potential, which increases neuronal excitability and allows for more spontaneous cell ...

  9. Pacemaker current - Wikipedia

    en.wikipedia.org/wiki/Pacemaker_current

    A similar current, termed I h (hyperpolarization-activated), has also been described in different types of neurons, where it has a variety of functions, including the contribution to control of rhythmic firing, regulation of neuronal excitability, sensory transduction, synaptic plasticity and more. [7]