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Bladder and breast cancer. squamous cell carcinoma of head and neck, gestational trophoblastic disease, acute leukaemias, non-Hodgkin lymphoma, osteosarcoma, brain tumours, graft-versus-host disease and systemic sclerosis.
The 2004 list was updated in 2010, 2012, and 2014. The current update (2016) adds 34 drugs, five of which have safe-handling rec-ommendations from the manufacturers. In 2014, a new format was developed for the list of hazardous drugs, as described below.
Preventing Occupational Exposures to Antineoplastic and Other Hazardous Drugs in Health Care Settings was published in September 2004. In Appendix A of the Alert, NIOSH identified a sample list of major hazardous drugs.
The format for the 2014 list was revised to include three groups of hazardous drugs: (1) Antineoplastic drugs; (2) Non-antineoplastic hazardous drugs; and (3) Drugs with reproductive effects. The current update (2016) adds 34 drugs and includes a review of the 2004 list.
The latest publication, entitled NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings, 2016 (2016 Update), covered all new approved drugs and drugs with new warnings through December 2013.
Antineoplastics or anticancer drugs affect the process of cell division i.e. are antiproliferative. They damage the DNA and initiate apoptosis, preventing the development and spread of neoplastic cells.
The current update (2016) adds 34 drugs, five of which have safe-handling recommendations from the manufacturers. In 2014, a new format was developed for the list of hazardous drugs, as described in this document.
The peer reviewers’ comments in the tables below are organized by drug. Both generic and proprietary drug names are provided for ease of determining the drug reviewed and criteria. For each drug, the comments received are organized by the categories in the NIOSH Hazardous Drug definition: carcinogenicity, genotoxicity, organ toxicity at low ...
The National Institute for Occupational Safety and Health (NIOSH) of the Centers for Disease Control and Prevention (CDC), announces the availability of the following publication: NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings 2016 [2016-161].
This article includes a list of common types of antineoplastic drugs, with examples. It discusses the basics of antineoplastic drug side effects. It describes the differences and similarities among antineoplastic medications, chemotherapy, and immunotherapy.