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A total review of metformin use during pregnancy compared to insulin alone found good short-term safety for both the mother and baby, but safety in the longer term is unclear. [61] Several observational studies and randomized controlled trials found metformin to be as effective and safe as insulin for the management of gestational diabetes.
The dog's body weight should be determined and calculated once every two weeks using weight scale. [48] The daily caloric requirement by the dog's body and BCS should also be determined using a scale as part of dietary management in maintaining average body weight. The protein intake by the dog should also be considered and checked twice a month.
Generally speaking, GLP-1s, GIP/GLP-1s, and metformin are considered safe and effective when used as prescribed. That said, no medication is without side effects.
As noted, timing your metformin dosage is crucial for mitigating the risk — and overall severity — of side effects. But what are those side effects exactly? The most common side effects of ...
Metformin treatment in pregnancy is not safe. [91] In 2007, the Royal College of Obstetricians and Gynaecologists also recommended against the use of the drug to prevent miscarriage. [ 90 ] Thrombophilias or defects in coagulation and bleeding were once thought to be a risk of miscarriage but have been subsequently questioned. [ 92 ]
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
The most common side-effects are upper respiratory tract infection, diarrhea, combined edema/peripheral edema and headache, respectively. Most clinical adverse events were similar between groups treated with pioglitazone in combination with metformin and those treated with pioglitazone monotherapy. [medical citation needed]
As with anything pregnancy-related, speaking to a healthcare provider is your best bet. They can assess your situation and explain your choices to help you find the best treatment plan.
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