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In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure O=P(OR) 3, a central phosphate molecule with alkyl or aromatic substituents. [1] They can be considered as esters of phosphoric acid. Organophosphates are best known for their use as pesticides.
Pesticide degradation is the process by which a pesticide is transformed into a benign substance that is environmentally compatible with the site to which it was applied. Globally, an estimated 1 to 2.5 million tons of active pesticide ingredients are used each year, mainly in agriculture .
Organophosphorus chemistry is the scientific study of the synthesis and properties of organophosphorus compounds, which are organic compounds containing phosphorus. [1] They are used primarily in pest control as an alternative to chlorinated hydrocarbons that persist in the environment.
The minimum survival time was 6 hours for females and 3 hours for males, while the maximum time of death was 3 days for females and 7 days for males. The LD50 was 245 mg /kg for males and 62 mg/kg for females. Skin contact with organophosphates, in general, may cause localized sweating and involuntary muscle contractions.
Persistent organic pollutants (POPs) are compounds that resist degradation and thus remain in the environment beyond their intended term. Some pesticides, including aldrin, chlordane, DDT, dieldrin, endrin, heptachlor, hexachlorobenzene, mirex, and toxaphene, are considered POPs. Some POPs have the ability to volatilize and travel great ...
Glyphosate (IUPAC name: N-(phosphonomethyl)glycine) is a broad-spectrum systemic herbicide and crop desiccant.It is an organophosphorus compound, specifically a phosphonate, which acts by inhibiting the plant enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSP).
Parathion, also called parathion-ethyl or diethyl parathion, is an organophosphate insecticide and acaricide.It was originally developed by IG Farben in the 1940s. It is highly toxic to non-target organisms, including humans, so its use has been banned or restricted in most countries.
In a study published in Genome Biology, [6] researchers demonstrated the gut microbiota mediated diabetogenic effect of organophosphate insecticides. They used monocrotophos as the prototypical organophosphate in their study and showcased that during chronic intake, monocrotophos is degraded by the gut microbiota and the end products are converted to glucose via gluconeogenesis that account ...
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