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Malassezia furfur is a fungus that lives on the superficial layers of the dermis.It generally exists as a commensal organism forming a natural part of the human skin microbiota, but it can gain pathogenic capabilities when morphing from a yeast to a hyphal form during its life cycle, through unknown molecular changes. [2]
PSK is a protein polysaccharide consisting of a beta-glucan β-1,4 main chain with β-1,3 and β-1,6 side chains. The approximate molecular weight of PSK is 100,000 Da, and the protein component is reported at the β-1,6 side chain. [10] PSK is isolated from the "CM-101" strain of Trametes versicolor.
Mucinoses are a group of conditions caused by dermal fibroblasts producing abnormally large amounts of mucopolysaccharides. [34] Acral persistent papular mucinosis; Atypical lichen myxedematosus (intermediate lichen myxedematosus) Atypical tuberous myxedema (Jadassohn–Dosseker syndrome) Cutaneous focal mucinosis
An estimated 1.6 million deaths from fungal disease were reported in 2017. [30] The figure has been rising, with an estimated 1.7 million deaths from fungal disease reported in 2020. [12] Fungal infections also constitute a significant cause of illness and mortality in children. [31]
Conditions caused by mutations in or antibodies against junctional proteins found within the epidermis of the human integumentary system. Junctional protein Condition(s) Desmocollin 1: Subcorneal pustular dermatosis type of IgA pemphigus: Desmocollin 2: Arrhythmogenic right ventricular dysplasia (ARVD) Desmoglein 1: Striate palmoplantar keratoderma
Aspergillosis is the group of diseases caused by Aspergillus. The symptoms include fever, cough, chest pain or breathlessness. Usually, only patients with weakened immune systems or with other lung conditions are susceptible. [1] The spores of Aspergillus fumigatus are ubiquitous in the atmosphere. A. fumigatus is an opportunistic pathogen. It ...
Fungi cause the majority of plant diseases, which in turn cause serious economic losses. Sometimes, as in the Great Irish Famine of 1845–1849, fungal diseases of plants, in this case potato blight caused by Phytophthora, result in large-scale human suffering. Fungi are similarly the main cause of economic losses of timber in buildings.
The other primary mycotoxin groups found in mushrooms include: orellanine, monomethylhydrazine, disulfiram-like, hallucinogenic indoles, muscarinic, isoxazole, and gastrointestinal (GI)-specific irritants. [28] The bulk of this article is about mycotoxins that are found in microfungi other than poisons from mushrooms or macroscopic fungi. [21]