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Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy in which androgens, often testosterone, are supplemented or replaced. It typically involves the administration of testosterone through injections, skin creams, patches, gels, pills, or subcutaneous pellets.
Testosterone is in the androgen family of medications. [9] Testosterone was first isolated in 1935, and approved for medical use in 1939. [12] [13] Rates of use have increased three times in the United States between 2001 and 2011. [14] It is on the World Health Organization's List of Essential Medicines. [15] It is available as a generic ...
Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
Testosterone enanthate is used primarily in androgen replacement therapy. [4] [15] It is the most widely used form of testosterone in androgen replacement therapy. [4]The medication is specifically approved, in the United States, for the treatment of hypogonadism in men, delayed puberty in boys, and breast cancer in women. [16]
Testosterone cypionate: Depo-Testosterone: Oil solution: 50–250 mg 1x/1–4 weeks Testosterone isobutyrate: Agovirin Depot: Aqueous suspension: 50–100 mg 1x/1–2 weeks Testosterone phenylacetate b: Perandren, Androject: Oil solution: 50–200 mg 1×/3–5 weeks Mixed testosterone esters: Sustanon 100, Sustanon 250: Oil solution: 50–250 ...
Testosterone esters were synthesized for the first time in 1936, and were found to have greatly improved potency relative to testosterone. [12] Among the esters synthesized, testosterone propionate was the most potent, and for this reason, was selected for further development, subsequently being marketed. [ 12 ]
Testosterone phenylpropionate: Oil solution: Testolent: 8 days Testosterone isobutyrate: Aqueous suspension: Agovirin Depot, Perandren M: 14 days Mixed testosterone esters a: Oil solution: Triolandren: 10–20 days Mixed testosterone esters b: Oil solution: Testosid Depot: 14–20 days Testosterone enanthate: Oil solution: Delatestryl: 14–28 ...
Testosterone can be taken by a variety of different routes of administration. [2] [3] These include oral, buccal, sublingual, intranasal, transdermal (gels, creams, patches, solutions), vaginal (creams, gels, suppositories), rectal (suppositories), by intramuscular or subcutaneous injection (in oil solutions or aqueous suspensions), and as a subcutaneous implant.
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