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The pKa of KHP is 5.4, so its pH buffering range would be 4.4 to 6.4; however, due to the presence of the second acidic group that bears the potassium ion, the first pKa also contributes to the buffering range well below pH 4.0, which is why KHP is a good choice for use as a reference standard for pH 4.00.
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The monopotassium salt, potassium hydrogen phthalate is a standard acid in analytical chemistry. Typically phthalate esters are prepared from the widely available phthalic anhydride . Reduction of phthalic acid with sodium amalgam in the presence of water gives the 1,3-cyclohexadiene derivative.
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Phthalates (US: / ˈ θ æ l eɪ t s / UK: / ˈ θ ɑː l eɪ t s ˌ ˈ f θ æ l ɪ t s / [1] [2]), or phthalate esters, are esters of phthalic acid. They are mainly used as plasticizers , i.e., substances added to plastics to increase their flexibility, transparency, durability, and longevity.
Folpet, a phthalimide, is a commercial fungicide. [3]Phthalimide is used as a precursor to anthranilic acid, a precursor to azo dyes and saccharin. [2]Alkyl phthalimides are useful precursors to amines in chemical synthesis, especially in peptide synthesis where they are used "to block both hydrogens and avoid racemization of the substrates". [4]
It is a phthalate and is the diester of phthalic acid and the 10-carbon branched-chain alcohol 2-propylheptanol. This colorless, viscous liquid is used for softening PVC plastics and is a general purpose PVC plasticizer . [ 2 ]
Potassium phthalimide is a chemical compound of formula C 8 H 4 KNO 2. It is the potassium salt of phthalimide , and usually presents as fluffy, very pale yellow crystals. It can be prepared by adding a hot solution of phthalimide in ethanol to a solution of potassium hydroxide in ethanol; the desired product precipitates.