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Physiological functions at high altitude are not normal and evidence also shows impairment of neuropsychological function, which has been implicated in mountaineering and aviation accidents. [1] Methods of mitigating the effects of the high altitude environment include oxygen enrichment of breathing air and/or an increase of pressure in an ...
High-altitude adaptation in humans is an instance of evolutionary modification in certain human populations, including those of Tibet in Asia, the Andes of the Americas, and Ethiopia in Africa, who have acquired the ability to survive at altitudes above 2,500 meters (8,200 ft). [1]
Altitude sickness, the mildest form being acute mountain sickness (AMS), is a harmful effect of high altitude, caused by rapid exposure to low amounts of oxygen at high elevation. [ 1 ] [ 2 ] [ 3 ] People's bodies can respond to high altitude in different ways.
High-altitude cerebral edema (HACE) is a medical condition in which the brain swells with fluid because of the physiological effects of traveling to a high altitude. It generally appears in patients who have acute mountain sickness and involves disorientation, lethargy, and nausea among other symptoms.
Aviation physiology can also include the effect in humans and animals exposed for long periods of time inside pressurized cabins. [2] The other main issue with altitude is hypoxia, caused by both the lack of barometric pressure and the decrease in oxygen as the body rises. [3]
Many deaths in high-altitude mountaineering have been caused by the effects of the death zone, either directly by the loss of vital functions or indirectly by poor decisions made under stress (e.g., not turning back in deteriorating conditions, or misreading the climbing route), or physical weakening leading to accidents (e.g., falls).
The Armstrong limit or Armstrong's line is a measure of altitude above which atmospheric pressure is sufficiently low that water boils at the normal temperature of the human body. Exposure to pressure below this limit results in a rapid loss of consciousness, followed by a series of changes to cardiovascular and neurological functions, and ...
Altitude research gets round this by studying the effects of oxygen deprivation on otherwise healthy people. Travelling to high altitude is often used as a way of studying the way the body responds to a shortage of oxygen. It is difficult and prohibitively expensive to conduct some of this research at sea level.
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