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  2. Sertraline - Wikipedia

    en.wikipedia.org/wiki/Sertraline

    Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]

  3. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    Macrophages can release cytokines and other chemicals to cause an inflammatory response. Peripheral inflammation can induce an inflammatory response in microglia and can cause neuroinflammation. SSRIs inhibit proinflammatory cytokine production which leads to less activation of microglia and peripheral macrophages.

  4. Paradoxical reaction - Wikipedia

    en.wikipedia.org/wiki/Paradoxical_reaction

    Naltrexone blocks the opioid receptors, acting opposite to most opioid pain medications. [22] It can be used to negate the effects of opioid painkillers. At doses around one-tenth of the typical dose, naltrexone has been used for pain relief. Low-dose naltrexone is believed to have an anti-inflammatory effect. This is an off-label use and not ...

  5. Can Zoloft & Other SSRIs Cause "Intimate" Side Effects?

    www.aol.com/zoloft-other-ssris-cause-intimate...

    Below is an explanation of how medications such as Zoloft can cause intimate side effects like ED and low libido. It also includes some practical techniques that you can use to prevent ED and stay ...

  6. Serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin_reuptake_inhibitor

    Additionally, some clinically used drugs such as chlorpheniramine, dextromethorphan, and methadone possess SRI properties secondarily to their primary mechanism of action(s) and this contributes to their side effect and drug interaction profiles.

  7. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/switching-antidepressants-safety...

    Since some tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs) can cause harmful interactions if used within 14 days of starting treatment with other antidepressants, you may ...

  8. Serotonin syndrome - Wikipedia

    en.wikipedia.org/wiki/Serotonin_syndrome

    The cause of serotonin toxicity or accumulation is an important factor in determining the course of treatment. Serotonin is catabolized by monoamine oxidase A in the presence of oxygen , so if care is taken to prevent an unsafe spike in body temperature or metabolic acidosis, oxygenation will assist in dispatching the excess serotonin.

  9. FDA approves new pain medication as an alternative to ... - AOL

    www.aol.com/news/fda-approves-pain-medication...

    Acute pain is something more than 80 million Americans fill prescriptions to treat each year, according to Vertex. As opposed to chronic pain, which can last well after an injury or illness has ...

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