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Terazosin, sold under the brand name Hytrin among others, is a medication used to treat symptoms of an enlarged prostate and high blood pressure. [1] For high blood pressure, it is a less preferred option. [1] It is taken by mouth. [1] Common side effects include dizziness, headache, feeling tired, swelling, nausea, and low blood pressure with ...
Other drugs of the same family, doxazosin (Cardura) and terazosin (Hytrin), can also cause this phenomenon, though less frequently. The cause is not clear. It occurs more commonly in patients who are salt and fluid volume depleted (as happens due to the use of diuretics), or were using beta blockers. [4]
No dose adjustment is needed for patients with renal impairment. Terazosin is metabolised by the liver and is excreted by the biliary tract, so patients with moderate hepatic impairment should receive titrated doses of terazosin witch caution. Patients with severe hepatic impairment should not take terazosin due to lack of clinical data. [39] [42]
Alfuzosin, sold under the brand name Uroxatral among others, is a medication of the α 1 blocker class. It is used to treat benign prostatic hyperplasia (BPH). [1]As an antagonist of the α 1-adrenergic receptor, it works by relaxing the muscles in the prostate and bladder neck, making urination easier.
Prazosin is active after taken by mouth and has a minimal effect on cardiac function due to its α 1-adrenergic receptor selectivity.When prazosin is started, however, heart rate and contractility can increase in order to maintain the pre-treatment blood pressures because the body has reached homeostasis at its abnormally high blood pressure.
Treprostinil, sold under the brand names Remodulin for infusion, Orenitram for oral, and Tyvaso for inhalation, is a vasodilator that is used for the treatment of pulmonary arterial hypertension.
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Lisinopril/amlodipine is a combination of two agents which both act to induce vascular smooth muscle relaxation to lower blood pressure in distinct ways: [1]. Lisinopril inhibits angiotensin converting enzyme (ACE), the enzyme responsible for converting angiotensin I into angiotensin II (a vasoconstrictor).