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  2. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Remember, tadalafil 5-milligram side effects tend to be less severe than those experienced with 10- or 20-milligram dosages. Your provider may recommend adjusting your Cialis dosage if you’re ...

  3. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    Tadalafil is available in several dosages, from a minimum dosage of 2.5mg (milligrams) all the way up to a 20mg per tablet, the maximum dose of tadalafil in 24 hours. Tadalafil 10mg: Typical ...

  4. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Tadalafil. The active ingredient in Cialis, tadalafil is a long-lasting medication that can provide relief from ED for up to 36 hours. Vardenafil. The active ingredient in Levitra, vardenafil can ...

  5. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. [ 5 ] [ 6 ] [ 8 ] It is taken by mouth . [ 8 ]

  6. Pulmonary hypertension - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_hypertension

    Tadalafil is taken orally, as well as sildenafil, and it is rapidly absorbed (serum levels are detectable at 20 minutes). The T 1/2 (biological half-life) hovers around 17.5 hours in healthy subjects. [85] Moreover, if we consider pharmacoeconomic implications, patients that take tadalafil would pay two-thirds of the cost of sildenafil therapy ...

  7. Ototoxic medication - Wikipedia

    en.wikipedia.org/wiki/Ototoxic_medication

    Common drug examples include sildenafil, vardenafil and tadalafil. The enzyme PDE-5, found in the corpus cavernosum smooth muscle, is responsible for degrading cyclic guanosine monophosphate (cGMP) to 5-GMP. Inhibitors of this enzyme compete with cGMP for binding sites, which in turn increases the level of cGMP in smooth muscles.

  8. Is It Safe to Take Cialis Daily? - AOL

    www.aol.com/safe-cialis-daily-115900442.html

    Using Cialis or generic tadalafil as needed is a good option if you typically have intimacy a few times per week — for example, every other day. Since it lasts for a long time, you can take ...

  9. Pharmacokinetics - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics

    Total drug exposure is most often estimated by area under the curve (AUC) methods, with the trapezoidal rule (numerical integration) the most common method. Due to the dependence on the length of x in the trapezoidal rule, the area estimation is highly dependent on the blood/plasma sampling schedule.