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This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .
Although SJS can be caused by viral infections and malignancies, the main cause is medications. [14] A leading cause appears to be the use of antibiotics , particularly sulfa drugs . [ 13 ] [ 15 ] Between 100 and 200 different drugs may be associated with SJS. [ 16 ]
[6] [7] The drugs most commonly triggering the SJS, TEN, and SJS/TEN spectrum of disorders are anti-infective sulfonamides, anticonvulsants (e.g. carbamazepine and lamotrigine), non-steroidal anti-inflammatory drugs, allopurinol, nevirapine, and chlormezanone. Allopurinol appears in some studies to be the most common instigator of these disorders.
People with SJS or TEN caused by a medication have a better prognosis the earlier the causative medication is withdrawn. [11] Loss of the skin leaves patients vulnerable to infections from fungi and bacteria, and can result in sepsis, the leading cause of death in the disease. [13]
Allopurinol is one of the drugs commonly known to cause Stevens–Johnson syndrome and toxic epidermal necrolysis, two life-threatening dermatological conditions. [23] More common is a less-serious rash that leads to discontinuing this drug. [23]
Allergy medications may cause brain damage, increase dementia risk because of course they can, everything can. Alex Lasker. Updated July 14, 2016 at 10:50 PM.
However, just a single glass of grapefruit juice can block this enzyme and interfere with your body's process of breaking down the medication. "This causes medication levels to remain higher and ...
Medication side effect, ... (SjS, SS)) is a long-term ... Some medications can cause symptoms similar to those of Sjögren's syndrome. [citation needed]
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