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Chlorpromazine is in the typical antipsychotic class, [ 6 ] and, chemically, is one of the phenothiazines. Its mechanism of action is not entirely clear but is believed to be related to its ability as a dopamine antagonist. [ 6 ] It has antiserotonergic and antihistaminergic properties.
Typical antipsychotic. Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia). Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions.
Lunesta (eszopiclone) – a non-benzodiazepine hypnotic. Luvox (fluvoxamine) – an antidepressant of the SSRI class. Loxitane (loxapine) – an antipsychotic used in the treatment of mood disorders and schizophrenia. Lyrica (pregabalin) – treats nerve and muscle pain, including fibromyalgia. It can also treat seizures.
Used to treat psychotic disorders including schizophrenia, acute manic episodes, and maintenance of bipolar disorder. Used as an adjunct to antidepressant therapy, either alone or in combination with fluoxetine as Symbyax. Quetiapine (Seroquel) – Of the dibenzothiazepine class of atypical antipsychotics.
It acts similar to chlorpromazine and causes sedation. [3] It has predominantly anticholinergic side effects, though extrapyramidal side effects are not uncommon. It belongs to the typical antipsychotic and phenothiazine class of drugs.
The first major tranquilizer or antipsychotic medication, chlorpromazine (Thorazine), a typical antipsychotic, was discovered in 1951 and introduced into clinical practice shortly thereafter. Clozapine (Clozaril), an atypical antipsychotic, fell out of favor due to concerns over drug-induced agranulocytosis.
Prochlorperazine, formerly [5] sold under the brand name Compazine among others, is a medication used to treat nausea, migraines, schizophrenia, psychosis and anxiety. [6][7][8][9] It is a less preferred medication for anxiety. [6] It may be taken by mouth, rectally, injection into a vein, or injection into a muscle.
The first widely used psychiatric drug, by 1955 it was already generating significant revenue as an antipsychotic. [61] Research chemists quickly began to explore other derivatives of chlorpromazine. The first TCA reported for the treatment of depression was imipramine, a dibenzazepine analogue of chlorpromazine code-named G22355. It was not ...