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  2. Targeted drug delivery - Wikipedia

    en.wikipedia.org/wiki/Targeted_drug_delivery

    Targeted drug delivery. Targeted drug delivery, sometimes called smart drug delivery, [1] is a method of delivering medication to a patient in a manner that increases the concentration of the medication in some parts of the body relative to others. This means of delivery is largely founded on nanomedicine, which plans to employ nanoparticle ...

  3. Immunoliposome therapy - Wikipedia

    en.wikipedia.org/wiki/Immunoliposome_Therapy

    Immunoliposome therapy is a targeted drug delivery method that involves the use of liposomes (artificial lipid bilayer vesicles) coupled with monoclonal antibodies to deliver therapeutic agents to specific sites or tissues in the body. [1] The antibody modified liposomes target tissue through cell-specific antibodies with the release of drugs ...

  4. Liposome - Wikipedia

    en.wikipedia.org/wiki/Liposome

    Until recently, the clinical uses of liposomes were for targeted drug delivery, but new applications for the oral delivery of certain dietary and nutritional supplements are in development. [31] This new application of liposomes is in part due to the low absorption and bioavailability rates of traditional oral dietary and nutritional tablets ...

  5. Nanocarrier - Wikipedia

    en.wikipedia.org/wiki/Nanocarrier

    Drug-loaded polymeric micelle formed from self-assembly of amphiphilic block copolymers in aqueous media. Drug-loaded polymeric micelles with various targeting functions. (A) Antibody-targeted micelles (B) ligand-targeted micelles (C) Micelles with cell-penetrating function. A nanocarrier is nanomaterial being used as a transport module for ...

  6. Enhanced permeability and retention effect - Wikipedia

    en.wikipedia.org/wiki/Enhanced_permeability_and...

    The enhanced permeability and retention (EPR) effect is a controversial concept [1][2] by which molecules of certain sizes (typically liposomes, nanoparticles, and macromolecular drugs) tend to accumulate in tumor tissue much more than they do in normal tissues. [3][4][5] The general explanation that is given for this phenomenon is that, in ...

  7. Drug delivery - Wikipedia

    en.wikipedia.org/wiki/Drug_delivery

    Drug delivery is a concept heavily integrated with dosage form and route of administration, the latter sometimes being considered part of the definition. [9] While route of administration is often used interchangeably with drug delivery, the two are separate concepts. Route of administration refers to the path a drug takes to enter the body ...

  8. Lipid bilayer - Wikipedia

    en.wikipedia.org/wiki/Lipid_bilayer

    These drug-loaded liposomes travel through the system until they bind at the target site and rupture, releasing the drug. In theory, liposomes should make an ideal drug delivery system since they can isolate nearly any hydrophilic drug, can be grafted with molecules to target specific tissues and can be relatively non-toxic since the body ...

  9. Stimuli-responsive drug delivery systems - Wikipedia

    en.wikipedia.org/wiki/Stimuli-responsive_drug...

    Within the broad field of drug delivery, the development of stimuli-responsive drug delivery systems has created the ability to tune drug delivery systems to achieve more controlled dosing and targeted specificity based on material response to exogenous and endogenous stimuli. Endogenous stimuli consist of chemical, biological, and physical ...

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