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The stage when the human brain is developing is possibly the most sensitive time period to the effects of nicotine. [104] When the brain is being developed, activating or desensitizing nicotinic acetylcholine receptors by being exposed to nicotine can result in long-term developmental disturbances. [90]
Dementia is an umbrella term for a range of conditions that affect how the brain works, reducing the ability to remember, think and reason. It mainly affects older people and gets worse over time. Health and lifestyle factors such as high blood pressure and smoking are known to increase the risk of developing dementia. [65]
This is an accepted version of this page This is the latest accepted revision, reviewed on 7 January 2025. Circumstances, mechanisms, and factors of tobacco consumption on human health "Health effects of smoking" and "Dangers of smoking" redirect here. For cannabis, see Effects of cannabis. For smoking crack cocaine, see Crack cocaine § Health issues. "Smoking and health" redirects here. For ...
Smoker melanosis in a patient consuming 2 packs of cigarette per day. Smoking or the use of nicotine-containing drugs is the cause to Smoker's melanosis. [10] [11] Tar-components (benzopyrenes) are also known to stimulate melanocytes to melanin production, and other unknown toxic agents in tobacco may also be the cause.
Nicotine withdrawal is the main factor hindering smoking cessation. [52] A 2010 World Health Organization report states, "Greater nicotine dependence has been shown to be associated with lower motivation to quit, difficulty in trying to quit, and failure to quit, as well as with smoking the first cigarette earlier in the day and smoking more ...
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Nicotine could have cancer-promoting properties, therefore long-term use may not be harmless. [106] Nicotine may result in neuroplasticity variations in the brain. [163] Nicotine has been demonstrated to alter the amounts of brain-derived neurotrophic factor in humans. [272] Nicotine could make cancer therapies less effective. [273]
Smoking cessation, usually called quitting smoking or stopping smoking, is the process of discontinuing tobacco smoking. [1] Tobacco smoke contains nicotine , which is addictive and can cause dependence .