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Index inducer or just inducer predictably induce metabolism via a given pathway and are commonly used in prospective clinical drug-drug interaction studies. [ 4 ] Strong, moderate, and weak inducers are drugs that decreases the AUC of sensitive index substrates of a given metabolic pathway by ≥80%, ≥50% to <80%, and ≥20% to <50% ...
An enzyme inducer is a type of drug that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme. [1] [page needed] It is the opposite of an enzyme repressor.
Enzyme induction is a process in which a molecule (e.g. a drug) induces (i.e. initiates or enhances) the expression of an enzyme. Enzyme inhibition can refer to the inhibition of the expression of the enzyme by another molecule; interference at the enzyme-level, basically with how the enzyme works.
An inducer is the axial inlet portion of a centrifugal pump rotor, the function of which is to raise the inlet head by an amount sufficient to prevent significant cavitation in the following pump stage. [1]
Mutual inductance occurs when the magnetic field of an inductor induces a magnetic field in an adjacent inductor. Mutual induction is the basis of transformer construction. = where M is the maximum mutual inductance possible between 2 inductors and L 1 and L 2 are the two inductors. In general
Electromagnetic or magnetic induction is the production of an electromotive force (emf) across an electrical conductor in a changing magnetic field. Michael Faraday is generally credited with the discovery of induction in 1831, and James Clerk Maxwell mathematically described it as Faraday's law of induction .
In biology, an autoinducer is a signaling molecule that enables detection and response to changes in the population density of bacterial cells.Synthesized when a bacterium reproduces, autoinducers pass outside the bacterium and into the surrounding medium. [1]
The inducer can remove this repressor, turning genes back on. The operator is a section of DNA where the repressor binds to shut off certain genes; the promoter is the section of DNA where the RNA polymerase binds.