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Furthermore, Lambert et al. and Eshed et al. also indicates that neurofascin accumulates before Nav channels and is likely to have crucial roles in the earliest events associated with node of Ranvier formation. Thus, multiple mechanisms may exist and work synergistically to facilitate clustering of Nav channels at nodes of Ranvier.
An impulse (action potential) that originates from the SA node at a relative rate of 60–100 bpm is known as a normal sinus rhythm. If SA nodal impulses occur at a rate less than 60 bpm, the heart rhythm is known as sinus bradycardia. If SA nodal impulses occur at a rate exceeding 100 bpm, the consequent rapid heart rate is sinus tachycardia ...
The atrioventricular node or AV node electrically connects the heart's atria and ventricles to coordinate beating in the top of the heart; it is part of the electrical conduction system of the heart. [1] The AV node lies at the lower back section of the interatrial septum near the opening of the coronary sinus, and conducts the normal ...
Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
Diagram of a voltage-sensitive sodium channel α-subunit. G ... Beta 3 and beta 1 bind to neurofascin at Nodes of Ranvier in developing neurons. ... heart, skeletal ...
Myelinated axons only allow action potentials to occur at the unmyelinated nodes of Ranvier that occur between the myelinated internodes. It is by this restriction that saltatory conduction propagates an action potential along the axon of a neuron at rates significantly higher than would be possible in unmyelinated axons (150 m/s compared from 0.5 to 10 m/s). [1]
Diagram of the human heart, created by Wapcaplet in Sodipodi. Cropped by ~~~ to remove white space (this cropping is not the same as Wapcaplet's original crop). == See also == * Image:Diagram of the human heart.svg - original
The sinoatrial node (SA node) is the primary pacemaker of the heart. It is a region of cardiac muscle on the wall of the upper right atrium near to the superior vena cava entrance. The cells that make up the SA node are specialized cardiomyocytes known as pacemaker cells that can spontaneously generate cardiac action potentials.