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Romiplostim, sold under the brand name Nplate among others, is a fusion protein analog of thrombopoietin, a hormone that regulates platelet production. The most common side effects in adults include headache, infections of the nose and throat, and allergic (hypersensitivity) reactions such as rash, itching and rapid swelling under the skin. [ 1 ]
Romiplostim (trade name Nplate) is a thrombopoiesis stimulating Fc-peptide fusion protein (peptibody) that is administered by subcutaneous injection. Designated an orphan drug in 2003 under United States law, clinical trials demonstrated romiplostim to be effective in treating chronic ITP, especially in relapsed post-splenectomy patients.
Romiplostim (trade name Nplate, formerly AMG 531) was found to be safe and effective for the treatment of ITP in refractory patients, especially those who relapsed following splenectomy. [ 31 ] Heparin-induced thrombocytopenia
A vehicle registration plate, also known as a number plate (British English), license plate or licence plate (American English and Canadian English respectively), is a metal or plastic plate or plates attached to a motor vehicle or trailer for official identification purposes.
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The North American plate is a tectonic plate containing most of North America, Cuba, the Bahamas, extreme northeastern Asia, and parts of Iceland and the Azores.With an area of 76 million km 2 (29 million sq mi), it is the Earth's second largest tectonic plate, behind the Pacific plate (which borders the plate to the west).
Image source: The Motley Fool. Amgen (NASDAQ: AMGN) Q4 2024 Earnings Call Feb 04, 2025, 4:30 p.m. ET. Contents: Prepared Remarks. Questions and Answers. Call ...
They include: Amevive , Arcalyst , Enbrel , Nplate (romiplostim), Orencia and Nulojix . [40] Enbrel ( etanercept ) was the first successful IgG Fc-linked soluble receptor therapeutic and works by binding and neutralizing the pro-inflammatory cytokine, TNF-α.
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