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  2. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    ALS is the most common motor neuron disease in adults and the third most common neurodegenerative disease [61] after Alzheimer's disease and Parkinson's disease. [121] Worldwide the number of people who develop ALS yearly is estimated to be 1.9 people per 100,000 per year, while the number of people who have ALS at any given time is estimated ...

  3. Amyotrophic lateral sclerosis research - Wikipedia

    en.wikipedia.org/wiki/Amyotrophic_lateral...

    Using different BAC C9orf72 transgenic mouse model, they were able to study the symptoms of ALS, such as gait abnormalities, anxiety-like behavior, reduced grip strength, and even death rates. [8] Also, the denervation of motor neurons and dysfunction of neurons can be visualized using fluorescent markers to study the neurodegenerative disorder ...

  4. Primary lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Primary_lateral_sclerosis

    Motor neuron diseases develop when the nerve cells that control voluntary muscle movement degenerate and die, causing weakness in the muscles they control. PLS only affects upper motor neurons. [1] There is no evidence of the degeneration of spinal motor neurons or muscle wasting that occurs in amyotrophic lateral sclerosis (ALS).

  5. Multifocal motor neuropathy - Wikipedia

    en.wikipedia.org/wiki/Multifocal_motor_neuropathy

    Multifocal motor neuropathy (MMN) is a progressively worsening condition where muscles in the extremities gradually weaken.The disorder, a pure motor neuropathy syndrome, is sometimes mistaken for amyotrophic lateral sclerosis (ALS) because of the similarity in the clinical picture, especially if muscle fasciculations are present.

  6. FDA advisers vote against experimental ALS treatment ... - AOL

    www.aol.com/news/fda-advisers-vote-against...

    Federal health advisers voted overwhelmingly against an experimental treatment for Lou Gehrig’s disease at a Wednesday meeting prompted by years of patient efforts seeking access to the unproven ...

  7. List of people with motor neuron disease - Wikipedia

    en.wikipedia.org/wiki/List_of_people_with_motor...

    Public awareness of the disease gained prominence upon the diagnosis of baseball player Lou Gehrig, whose name would become an alternative title for the disease. Astrophysicist Stephen Hawking, whose ALS was diagnosed in 1963, had the disease for 55 years, the longest recorded time one had the disease. He died at the age of 76 in 2018.

  8. 'For Love & Life' tracks one man's journey from ALS diagnosis ...

    www.aol.com/news/love-life-tracks-one-mans...

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  9. ALS Therapy Development Institute - Wikipedia

    en.wikipedia.org/wiki/ALS_Therapy_Development...

    ALS TDI was founded as the ALS Therapy Development Foundation (ALS TDF) in 1999 by James Heywood, Robert Bonazoli, and Melinda Marsh Heywood after James' brother, Stephen Heywood, was diagnosed with the disease. [3] Dr. Tennore Ramesh joined ALS-TDF when his sister in law was diagnosed with ALS and setup the research facility and served as ...

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