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Here, PIP3 has been implicated in regulating synaptic strengthening and AMPA expression, contributing to long-term potentiation. Moreover, PIP3 suppression disrupts normal AMPA expression on the neuron membrane and instead leads to the accumulation of AMPA on dendritic spines, commonly associated with synaptic depression .
pip (also known by Python 3's alias pip3) is a package-management system written in Python and is used to install and manage software packages. [4] The Python Software Foundation recommends using pip for installing Python applications and its dependencies during deployment. [5] Pip connects to an online repository of public packages, called the ...
The Python Package Index, abbreviated as PyPI (/ ˌ p aɪ p i ˈ aɪ /) and also known as the Cheese Shop (a reference to the Monty Python's Flying Circus sketch "Cheese Shop"), [2]: 8 [3]: 742 is the official third-party software repository for Python. [4] It is analogous to the CPAN repository for Perl [5]: 36 and to the CRAN repository for R.
Microsoft Office 4.0 was released containing Word 6.0, Excel 4.0a, PowerPoint 3.0 and Mail in 1993. [142] Word's version number jumped from 2.0 to 6.0 so that it would have the same version number as the MS-DOS and Macintosh versions (Excel and PowerPoint were already numbered the same as the Macintosh versions).
A large number of PH domains have poor affinity for phosphoinositides and are hypothesized to function as protein binding domains. A Genome-wide look in Saccharomyces cerevisiae showed that most of the 33 yeast PH domains are indeed promiscuous in binding to phosphoinositides, while only one (Num1-PH) behaved highly specific . [ 12 ]
Ability Office – available for Windows; Google Workspace – available for Android, ChromeOS, iOS, iPadOS, Linux, macOS, online and Windows; Hancom Office – available for Windows
On 5 January 1975, the 12-bit field that had been used for dates in the TOPS-10 operating system for DEC PDP-10 computers overflowed, in a bug known as "DATE75". The field value was calculated by taking the number of years since 1964, multiplying by 12, adding the number of months since January, multiplying by 31, and adding the number of days since the start of the month; putting 2 12 − 1 ...
In The Heroes of Olympus, Apollo's Roman descendant Octavian promises the god many things for blessing his prophetic skills, which leads to the Olympians' distraction from the true threat of Gaia, and to the resurgence of Python. As a result, the Delphic Oracle ceases to function, effectively halting demigod quests, and Zeus punishes Apollo.