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Depressant. Not to be confused with depressogen. Depressants, colloquially known as " downers " or central nervous system (CNS) depressants, are drugs that lower neurotransmission levels, decrease the electrical activity of brain cells, or reduce arousal or stimulation in various areas of the brain. [1]
Antidepressants may be modestly helpful for treating people who have both depression and alcohol dependence, however, the evidence supporting this association is of low quality. [ 68 ] Bupropion is used to help people stop smoking. Antidepressants are also used to control some symptoms of narcolepsy. [ 69 ]
Atypical antipsychotics include: Amisulpride (Solian) – approved in low doses as a monotherapy for persistent depression. Lumateperone (Caplyta) – approved as a monotherapy for bipolar depression. Lurasidone (Latuda) – approved as a monotherapy for bipolar depression. Quetiapine (Seroquel) – approved as a monotherapy for bipolar depression.
In Wikidata. Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into ...
Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [2] It is used for the treatment of major depressive disorder, obsessive–compulsive disorder (OCD), anxiety, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. [2]
The pharmacology of antidepressants is not entirely clear. The earliest and probably most widely accepted scientific theory of antidepressant action is the monoamine hypothesis (which can be traced back to the 1950s), which states that depression is due to an imbalance (most often a deficiency) of the monoamine neurotransmitters (namely serotonin, norepinephrine and dopamine). [1]
Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants. TCAs were discovered in the early 1950s and were marketed later in the decade. [1] They are named after their chemical structure, which contains three rings of atoms. Tetracyclic antidepressants (TeCAs), which contain four rings of atoms, are ...
A review found a convergence of three phenomena: Chronic stress reduces synaptic and dendritic plasticity; Depressed subjects show evidence of impaired neuroplasticity (e.g. shortening and reduced complexity of dendritic trees) Anti-depressant medications may enhance neuroplasticity at both a molecular and dendritic level.
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