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267,500 (2015) [6] Peptic ulcer disease is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. [1][7] An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. [1] The most common symptoms of a duodenal ulcer are waking ...
Helicobacter pylori. (Marshall et al. 1985) Goodwin et al., 1989. Synonyms. Campylobacter pylori Marshall et al. 1985. Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, flagellated, helical bacterium. Mutants can have a rod or curved rod shape, that exhibit less virulence. [1][2] Its helical body (from which the ...
Hyperplasia of parietal cells causes an abnormal release of HCl into the duodenum, which causes the ulcers of the duodenum. Excessive HCl production also causes hyperperistalsis, [ 14 ] a condition marked by excessive rapidity of the passage of food through the stomach and intestine and inhibits the activity of lipase , causing severe fatty ...
The duodenal bulb is the site of duodenal ulcer occurrence. Duodenal ulcers are more common than gastric ulcers and - unlike gastric ulcers - are caused by increased gastric acid secretion. Duodenal ulcers are commonly located anteriorly, and rarely posteriorly. Anterior ulcers can be complicated by perforation, while the posterior ones bleed.
William Beaumont first demonstrates the acidity of the stomach and a relationship between acid levels and mood. [2] 1868 Kussmaul suggests using bismuth compounds, an antibacterial agent, to treat peptic ulcers (bismuth subsalicylate has since been used in many commercial drugs, including Pepto Bismol as part of antibacterial H. pylori ...
Zollinger–Ellison syndrome. Zollinger–Ellison syndrome (Z-E syndrome) is rare disease in which tumors cause the stomach to produce too much acid, resulting in peptic ulcers. Symptoms include abdominal pain and diarrhea. The syndrome is caused by a gastrinoma, a neuroendocrine tumor that secretes a hormone called gastrin. [2]
50,000 (2015) [5] Gastritis is the inflammation of the lining of the stomach. [1] It may occur as a short episode or may be of a long duration. [1] There may be no symptoms but, when symptoms are present, the most common is upper abdominal pain (see dyspepsia). [1]
Stomach ulcers commonly cause gnawing or burning pain in the stomach area. The pain can last from a few minutes to a few hours and may travel from the middle of the stomach to the neck, radiate to ...
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